ID A0A452J2H3_9SAUR Unreviewed; 975 AA.
AC A0A452J2H3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGAGP00000034607.1};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000034607.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000034607.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR AlphaFoldDB; A0A452J2H3; -.
DR STRING; 38772.ENSGAGP00000034607; -.
DR Ensembl; ENSGAGT00000039181.1; ENSGAGP00000034607.1; ENSGAGG00000024461.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF381; UNCONVENTIONAL MYOSIN-IG; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT DOMAIN 1..664
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 781..974
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT REGION 541..563
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 80..87
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 975 AA; 110877 MW; CDF87424A220C966 CRC64;
MSSGAVSGCE QTFPWDRADG AALASPGPQD TLAASGAEMA LALPSLLPQA SPCSHPPPAQ
AAKPRPSCCP LPILSVCLAG ESGAGKTEAS KYIMQYIAAI TNPSQREEVE RVKNVLLKSN
CVLEAFGNAK TNRNDNSSRF GKYMDINFDF KGDPTGGHIN NYLLEKVCPV SPPQLLLGTS
DAQLASLHLC RDPAAYRFTS EGASNNLLAS DQSNFKDVAD AMKVIGFSPE EIDSVYKILA
TILHLGNVSF VAEGDAVAIE NRELVSQLAE LTSTQPESLL RTLLYRAVAT GGGEVIEKGH
SAKEANYARD ACAKAIYERL FCWIVGRINT VIEVKNYDAR LHGKNTVIAV LDIYGFEIFD
SNSFEQFCIN YCNEKLQQLF IELILRQEQE EYQREGIEWQ HIEYFNNQII VDLVEQPHKG
IISILDEACL TGGQVTDAMF LESMNTKLGK HPHYTSRKLC ATDKSMEFGR DFRIKHYAGN
VTYSVEGFID KNKDTLFQDF KRLMYNSTDP VLRDMWPEGE VSITEVTKRP LTAATLFKNS
MVALVENLAS KEPYYVRCIK PNDQKSPLLF DAERCRHQVE YLGLLENVRV RRAGFAYRQP
YDRFLLRYKM TCEYTWPNHL MPTDQEATRA LIDQHGFQDD VAYGHTKLFI RMPQILFCLE
QERAQLIPII VLLLQKAWRG ALARRRCRYL RAIYTIMGHY RRHKVKTYLL ELVRRFQGVR
SMADYGKGVE WPDPPAVLAQ FQENSKLLFC RWRARQIVKN IPPSDMGQIQ AKVAAMEVLQ
GLRKDWGCQR NWGRDYLSSV AENPVMATQF TRRVQALRDK VHFSSVLFSC HVRKINRFNK
SRDRAILVTD QHLYKLEPRK QYKVMRTLPL SMVTGVSVTS CQDQLVVFHT KNHDDLVICF
HKMQPEEDNR VGELVGVLVH HFKTTKRELQ VRVSDCIQLS LRGRKRLVAV EMRHELAFPD
FGKSRDGFVL YCPRR
//
