ID A0A452J5A5_9SAUR Unreviewed; 3587 AA.
AC A0A452J5A5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=ELK domain-containing protein {ECO:0000259|SMART:SM01188};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000035641.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000035641.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
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DR STRING; 38772.ENSGAGP00000035641; -.
DR Ensembl; ENSGAGT00000040357.1; ENSGAGP00000035641.1; ENSGAGG00000025309.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0060090; F:molecular adaptor activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR InterPro; IPR028745; AKAP9/Pericentrin.
DR InterPro; IPR005539; ELK_dom.
DR InterPro; IPR019528; PACT_domain.
DR PANTHER; PTHR44981:SF1; A-KINASE ANCHOR PROTEIN 9; 1.
DR PANTHER; PTHR44981; PERICENTRIN-LIKE PROTEIN, ISOFORM F; 1.
DR Pfam; PF10495; PACT_coil_coil; 1.
DR SMART; SM01188; ELK; 6.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT DOMAIN 35..56
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 231..252
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 261..282
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 754..775
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 972..993
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT DOMAIN 1223..1243
FT /note="ELK"
FT /evidence="ECO:0000259|SMART:SM01188"
FT REGION 1331..1354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2112..2132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2428..2463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 26..69
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 98..242
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 321..397
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 421..512
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 548..575
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 709..736
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1221..1288
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1494..2110
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2156..2208
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2260..2329
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2802..2945
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3021..3132
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3272..3306
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3332..3359
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2428..2446
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2447..2463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3587 AA; 416527 MW; 4BACB7E5C7890E95 CRC64;
MGTVEELQKR CHKDSQFETD IVQRMELETQ RRLAQLQAEL DEMYGQQIVQ MKQELIKQHA
LEIEELLAQQ KIELEKTLNP CSSDNINEDQ VHLMNIAINE LNMKLQDANY QKEKIKQDLS
KQLEEISAEN SLQQTQIENL FQELTFAREQ IQRAKQTIMD KECRLNEADK YQLMIEDLKA
QLASASELRK ELELKHEAEV TNYKIKLEML EREKDEVLDR MAESQEAELE RLRTQLLFSH
EEELSKLRED LQQEHRINIE ILKNNLATHY KQQLEGTQNE MSQKIEAMQF EKDNLITKQS
QLLLEISKLK DLQQSVVNSK SEEMTLQIQE LQKEIDVLRQ EEKEKGTLEQ EVQELQLKTE
LLEKQMKEKE VSLQKKCTEL ETQNNLLIDE NRALEEKLKH ILVTSEENLI FTDSVNSKSE
DLDLQKRIEK LMAENEQLVK QDIELKAEIE RQKNTFSFAE KNFEASYQEL QEEYACLLKI
KADLEESKNK EEAEYKTKLK ALTEELQHLQ SYELVVLKTK SSIFEGSKED KICRAETFEV
GEVVEKDTTE LMEKLEVAQR EKVELSLRLS DLSEQLKLKH SEICQLSEEV KSLKQEKEQV
LVICKKLEVI ISHSQTENVN IFEQKTKYSN EEAQADAIPV SETRNLKFDS SNEFSEEIKV
REDNLSLCKD SDHRVTEKEI QQILNPEQQS LLDHLHQMTD TLEGETSLLA ITQHENDQLQ
QQLDILKSEQ ADLRLQMEAQ RICLSLVYSA HLDEVREYLK AEKENALCSL KEELICSNTQ
EMNELKKMHQ LELQTLKGQQ ADDEGKSTVM LIEKLSKAVS KECFRLTQLL YSVQSEQHSS
PVIISPGEQD IFHVPTFERK EPDIELPARR IQAQALQESM QILLSKIMEE YNRLMALHTQ
FMSDCKKAEE QQTSYVELEQ QTSYVELEHR KEEESSCLQM KTEGLQTPSQ DLIDYQFTDL
MVRASRWEEM ENLKTQLEGK HAQEIEHLRS YFQQQLKETE ERYTTEIIHL QNRLQDISES
PKDLSISAES QGNSKDIMQK MTQTESLYQQ SIDMAVEFPR EMESKGDMDI IQLLEKQYQE
RLEEETAKVI VSMSVAFAQQ TELARMARQE EESAQTQIVH KKEKCFESKK KCTEDELDGH
LIKEKKADIK HAEEFKPLSK ELSEESSEIS SLEEQLESSV NPGYMLELSK NEMRFPVLPF
SHDKELTVKE ISPYHEMATS STETSDQLLL YEERLEDMRQ ELVRQYQEHQ QATELLRQGH
MQQMERQKEN QEQLLAELDR LKVQLAESVS VEKDSLVTER ERMLLEELEL LKQHSVPGRG
KLHCELCNNS TQTQNENESQ TESKEYTFEG KDRGGKPEEI SLDILSKERH TLQKANNRLL
KILLEVVKTT VAIEETIGLH VLGLLDSPGK DPPSSKTVLW EAEAEQSLKP CVHVGFEKEE
PSSLYHGTDL GDDATMRWSG ITDEGLQLTQ HLTESGFAGA EIDPDNEELV LNISSRLQAA
VEKLLEAINE TSNQLEHAKV SQTELMRESF KKQQEATEFF KCREELQERL NEEVKAREQL
ALELSKAEGL IDGYADERAF LEKQIQEKTD IIDHLEQELL CTGNKLQELE AERQQIQEEK
ELLSRQKDAM KADAGPVEQR IVDAAVDAAS QAELLEETEK LMKEKIEVQR QAEKEYDDLQ
KQVKALETDV EEQVNRFIEL EQEKNAELTD LRQQNQALEK QLEKTRKFLD EQAIDREHER
DVFQQEIQKL EQQLKTPQRF QPINEHQTRE VEQLTNHLQE KTDKCSELLL SKEQLQRDIQ
ERNEEIEKLE CRIRELEQAL IISADNLQKV EERKQCGAAI VKGDLPLEVQ LQAEQEAVDR
KEKEITNLEE QLEQFREELE NKNEEVQQLH MQLEIQRKES TTRFQELEQE NKLFKDEMER
LGLVIQKSED TSIKDHCLVP GKLAQIMQEK EQEIDHLNEQ ITTLQQQLEI TTDNKVIEEK
NEHIRELEAQ IECLKSDQER VKKNSEEEIE QLNEVIEKLQ QELANIEQKE PVDVASIQED
ADSLKHELDT VLAEKEALKK QVEDNNVESS MTRNELEETK LKMNHLKKEL DILKREHERV
TEKYKRLLMK GDKAEVGDRS KDKSEKLEEA LNEKSPELLE NKIQFKSVEE NTKISISNME
IKLQHLQAAV KERESELCQC YNQIKDLKEQ AKVETEVLKK KILELEEILQ EKVAAALVSQ
VQLNAIQEQN KLRPRMQAFS KGAEEANKNT QTENVNPIAK EETESKLSVL TEKLSEMENQ
LARMYNNLEL EKENAEIAQK EAIKKENRLL ELQQLLEDIQ EKYKEEIKKT LKQGEVQTSE
VVKELTQSQG GSVFIAESEL EKIKAESAAA KEELSSYREK SEKLKEELMV RETSMTHLQE
ELHRVQDNLV EAEKKLADYM RKEEEIAELD SRKDVDKPDN VSTKDHSTFT RKSSSSQTDK
TMQINSSNQT LQVLVKNVEI QNDLQNEYSS EEVAEVIREF TYKIDQMQEL HAAEIMDMET
RHISESEALK REQIVAVQVL TEECNALKEV IETLRAKEGV PISGLPHTAS YMARDGCSSE
SSSDWSQGIY LTQSQGSDIV SEGIGDDDET STELLPKKIK GLLQAVHHEG VQVLSLTEFS
DSERDILSFK QGPESWLEER KTFLSTVSSL KDLITQMQLH RETEIYVDCE SPESVPDWRG
ELLHAVQQVF LREQDVLLAA FQTELAELVT KDAIVLMNQL EHRLQEQVIS QRTAMDFIQN
ADRRSLLMEI QILRTQMNNR KINPQREQEI DPKSQEILEY NMQQKQSQIL EMQVELHSVK
DRAAELQEQL NTERMMVSEL KNELAQAKLE LETTLKAQHK HFKDLETIRT EVKEKAAELD
MLKDTMANEQ KKSRELQWAL EKEKAKMEHS EERGREELED LKISLEDQKQ KNLQLNKLLE
QEKQLSGDLQ QKIESQEVLN AAQLSHERGH NSELQVLLES EKVRALEMSS ALEREKELCA
QLQSVEDKGQ DGTHKPTEEL LKDLQKRMDE KHDRIVELVN EMERYKLDSV QMRQQMEKER
QIQRKTLQTE QDANILAQKK VHELESKVEN LHWQLGEKRQ QVHKLEHETK KLQEIIQELQ
KKEQAREGKK EGERAMCQNL NETTWDTSNE RTRNWVLQQK MEGVEMNEST YPIPTEVKGE
GDLSEGSKVL ENIRQKLQNV SSKLKQLAHK AACRLQFETA DDDNFIEVQS NIEDVLLLLG
TLPGLSQLEE LKLALPPGAT ASSLTEKLLR QNAELTGLVS RLSEEKNNLR NAAMKLEEEL
RRYQQRGPCG DYSSRYSLDN GANIDTLIAS EREIWNREKL SLQKSLKQAD AELSKLRAEL
RSEAFLRELG SNSENAVLKI IYGKYLRAES FRKALIYQKK YLLLLVGGFQ ECEEATLALI
ARMGGQPSYT DLEIITHRSK GFTRFRSVVR VSIAISRMKF LVRRWHRVTG SDLISVSRDG
FSMNRGNELR PDSLAGGLEL YGEHRHSSDR SRSDLEYLRS PINSQHRYQG IHVDLSPASL
ACSQLQNYDP DRALTDYINR LEALQRRLGS IQSGSTSYTH LHSGVRR
//
