ID A0A452J5Q2_9SAUR Unreviewed; 1180 AA.
AC A0A452J5Q2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Exportin-4 {ECO:0000256|ARBA:ARBA00040444};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000035790.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000035790.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR AlphaFoldDB; A0A452J5Q2; -.
DR STRING; 38772.ENSGAGP00000035790; -.
DR Ensembl; ENSGAGT00000040519.1; ENSGAGP00000035790.1; ENSGAGG00000025383.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR044189; XPO4/7-like.
DR PANTHER; PTHR12596; EXPORTIN 4,7-RELATED; 1.
DR PANTHER; PTHR12596:SF1; EXPORTIN-4; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 991..1102
FT /note="Exportin-1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08767"
SQ SEQUENCE 1180 AA; 133770 MW; 4F39EFA67E9AA724 CRC64;
MAVVQCSFPV HSVWSTRRAR TLAQSKWTLL GRILRSQVFA QLEVNRCIGT APPSMVNNEQ
RQHAEHIFLS FRKSKSPFAV CKHILETSKV DYVLFQAATA IMEAVVREWI LLEKSSIESL
RTFLLTYVLQ RPNLQKYVRE QILLAVAVIV KRGSLDKSID CKSIFHEVSQ LISSGNPTVQ
TLACSILTAL LSEFSSSSKT SNIGLSMEFH GNCKRIFQED DLRQIFMLTV EVLQEFSRRE
NLNAQMSSVF QRYLALANQV LSWNFLPPNY ILLIHYIAMF ESSQNVMLKP TELWRETLLD
IRVMELFFTV HRKIREDTDM AQDSLQCLAQ LASLHGPVFP DEGSQVDYLA HFIEGLLNTI
NGIEIEDSEA MGISSVFSNL ITVFPRNVLT AIPNELFSSF VNCLTHLTCS FGRSAALEEV
LDKDDMVYME AYDKLLESWL TLVQDDKHFH KGFFTPHAVQ VFNSYIQCHL AAPDGTRNLT
ANGVASREEE EISELQEDDR DQFSDQLASV GMLGRIAAEH CIPLLTSLLE DRVTRLHGQL
QRHQQQLLAS PGSGSIDNKV LDDLYEDIHW LILVTGYLLA NDTQGETPLI PPEVMEYSIK
HSTEVDINTT LQILGSPGEK ASSIPGYNRT DSVIRLLSAI LRVSEVESRA IRADLTHLLS
PQMGKDIVWF LKRWAKTYLL VDEKLYDQIS LPFNTAFGAD TEGSQWIVGY LLEKVISNLA
VWSSEQDLAN DTVQLLVTLV ERRERANLVI QCENWWNLAK QFARRSPPLH FLSSSVQRTL
MKALVLGGFA HMDTDTKQQY WTEVLQPLQQ RFLNVINQEN FQQICQEEEV KQEITATLEA
LCGIAEATQI DNVAILFNFL MDFLTNCIGL MEVYKNTPET VNLIIEVFVE VAHKQICYLG
ESKAMNLYEA CLTLLQVYSK NNLGRQRIDV TAEEDQYQDL LLIMELLTNL LSKEFIDFSD
TDEVFRGQEP GQAANRSVSA ADVVLYGVNL VLPLMSQDLL KFPSLCNQYY KLITFICEIF
PEKIPQLPED LFKSLMYSLE LGMSSMSSEV CQLCLEALTP LAEQCAKAQE TDSSLFLATR
HFLKMVFDML VLQKHNTEMT TAAGEAFYTL VCLHQAEYSE LVETLLSSQQ DPVIYQRLAD
AFNKLTASST PPSLDRKQKM AFLKSLEEFM ANVGGLLCVK
//
