ID A0A452J657_9SAUR Unreviewed; 1954 AA.
AC A0A452J657;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGAGP00000035981.1};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000035981.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000035981.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR Ensembl; ENSGAGT00000040730.1; ENSGAGP00000035981.1; ENSGAGG00000025513.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd22729; FHA_KIF13A; 1.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF5; -; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM01052; CAP_GLY; 1.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020}.
FT DOMAIN 1..310
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 1841..1883
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
FT REGION 1885..1932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 322..367
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 565..592
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1064..1091
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1892..1929
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 60..67
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1954 AA; 218391 MW; 5C4456AA896DDE1D CRC64;
MTSVTALKPP KVFAFDYCFW SMDESNTTKY AGQEVVFKCL GEGILEKAFQ GYNACIFAYG
QTGSGKSFSM MGNAEQLGLI PRLCGALFQR ISVEENDSQT FKVEVSYMEI YNEKVRDLLD
PKGSRQSLKV REHKVLGPYV DGLSQLAVTN FEDIESLMSE GNKSRTVAAT NMNEESSRSH
AVFNIVVTQT LYDLQSGNSG EKVSKVSLVD LAGSERVSKT GAAGDRLKEG SNINKSLSTL
GLVISSLADQ AAGKGKNKFV PYRDSVLTWL LKDNLGGNSQ TAMIATISPS ADNYEETLST
LRYADRAKRI VNHAVVNEDP NARVIRELRE EVEKLKEQLS QAEALKAPEL KEKLEESEKL
IKELTVTWEE KLRKTEEIAQ ERQRQLESMG ISLESSGIKV GDDKCYLVNL NADPALNELL
VYYLKDHTRV GADTSQDIQL FGIGIQPEHC EIHIELDGEV SLTPKENARS CVNGTLVCTA
TQLWHGDRIL WGNNHFFRIN LPKRKRRDWL KDFEKETVLA EHDLDATSEA SSEPDYNYEF
AQMEVIMKTL NSNDPVQNVV QILEKQYLEE KQSALEEQRL MYERELEQLR QQLSPERQHQ
HGSDRLSYTA QTVQQKVNIW TEERDELFRQ SLAKLREQIV KANTLVREAN FLAEEMNKLT
DYQVTLQIPA ANLSANRKRG AIVSEPAIQV RRKEKGTQVW TIEKLENKLI DMRDLYQEWK
EKVPEIRKLI GKKGDPFYEA QENHILIGVA NVFLECLFYD VKLQYAVPII SQQGEVAGRL
HVEVMRVTGV VPERVAEGDD SSENSSESGS LEIMDSNGEI IHRAKKLTCR VKIKEATGLP
LNLSNFVFCQ YAFWDQCEST VAAPVVDPDV PSPQSKEAQF TVTFSHCKDY VVNVSEEFLE
FISEGALAIE VWGHRCTGNG SSIWEVDSLH AKTRTLRDRW SEVTRRIEMW ISIQELNEMG
EYTAVELHQA KDVNTGGIFQ LRQGHSRRVQ VTVKPVQHSG TLPLMVEAIL SVSIGCVTAR
STKLQRGLDS YQRDDVDDGD MDSYQEEDLN CVRERWSDAL IKRREYLDEQ IKKISNKQEK
TEDEIEREAR LLEQWMGLTE ERNAVLVPAP GSGIPGAPAD WTPPSGMETH IPVLFLDLNA
DDLSANEQLV GPHASGVNSI LPKEHGSQFF YLPIIKHSDD EVSATAAWDS SVHDSVHLNR
VTPQNERIYL IVKITVQLSH PAAMELVLRK RIAANIYNKQ SFTQSLKRRI SLKNIFYSCG
VTYEIVSNIP KATEEIEDRE TLALMAARTE NEGTSDGETY IEKYTRGVLQ VENILSLERL
RQAVTVKEAL STKARHIRRS ISTPNVHNVS SSRLDVFGCD EDDKGWSESH LDISDCSSSY
QDVSCYGTLP RDSPRRNKDA GGCISETPHA LMASPFKAFS PQPPKFFKPL MPVKEEHKRK
IPLETRPLLS QESMPSTQVH NAGCVVPSGS NASSMPVENN SIHEEKIDSD EEDSELEAIN
KKLISSQGFH NFQPYVPEEF ADFSVYNASL ENTEWFSTKT DFMNSRVLEK EVSRSPTASS
ITSGYISHSA SNATLSDMLV PCSDSTDQLA NQMKDLDSSD QSGPCLAYVL RSLNKEFPER
GLAKDKIHVS PLKENSALAK EIPPSLNTTD KNSEMLHRAD SCSGLDSSTS KNMRDKIEFS
SREATTEHTS DVLEDHSFTE FMGVEDGKDF DQSVDPKLCS TGSSKGRKEI PVAGVDSASD
LSQNTYKEGI RLGQLDSVAV GYQLSNAIEN PLFSVLVKET SYCQTYPDSS LNDFITKNHL
DVSDSEDGAS AEEAHTLPSW VAVGEQVCVG SNKTGTVRYI GPVDFSAGIW VGVELSVQLG
KHDGTVKGRE YFHCRPRHGL FVRPGRLSKA PASTKRCSST SQSQASSSLE KRKSSVLQGS
SSSSKAGEAP LCQSGDAVAS AFSRKQENRK SWIK
//
