ID A0A452J681_9SAUR Unreviewed; 1793 AA.
AC A0A452J681;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGAGP00000035997.1};
OS Gopherus agassizii (Agassiz's desert tortoise).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Testudinidae; Gopherus.
OX NCBI_TaxID=38772 {ECO:0000313|Ensembl:ENSGAGP00000035997.1, ECO:0000313|Proteomes:UP000291020};
RN [1] {ECO:0000313|Proteomes:UP000291020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=28562605;
RA Tollis M., DeNardo D.F., Cornelius J.A., Dolby G.A., Edwards T.,
RA Henen B.T., Karl A.E., Murphy R.W., Kusumi K.;
RT "The Agassiz's desert tortoise genome provides a resource for the
RT conservation of a threatened species.";
RL PLoS ONE 12:e0177708-e0177708(2017).
RN [2] {ECO:0000313|Ensembl:ENSGAGP00000035997.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
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DR Ensembl; ENSGAGT00000040750.1; ENSGAGP00000035997.1; ENSGAGG00000025503.1.
DR Proteomes; UP000291020; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 2.60.220.30; -; 2.
DR Gene3D; 2.60.40.2660; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 5.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR040745; Ankyrin_UPA.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR000906; ZU5_dom.
DR PANTHER; PTHR24198; ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24198:SF173; ANKYRIN-3; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 6.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF17809; UPA_2; 1.
DR Pfam; PF00791; ZU5; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 21.
DR SMART; SM00005; DEATH; 1.
DR SMART; SM00218; ZU5; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 19.
DR PROSITE; PS50088; ANK_REPEAT; 19.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS51145; ZU5; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000291020};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 48..80
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 81..113
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 114..146
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 147..171
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 209..241
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 242..274
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 275..307
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 308..340
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 341..373
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 374..406
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 407..439
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 440..472
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 473..505
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 506..538
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 591..623
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 624..656
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 657..689
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 690..722
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 723..755
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 890..1045
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 1047..1193
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 1371..1441
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT REGION 851..881
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1793 AA; 195585 MW; DE93D2B1E777E957 CRC64;
MAVQKGRSGP DVAADAATSF LRAARSGNLD KALDHLRNGV DINTCNQNGL NALHLASKEG
HVKMVAELLH KEIVLETTTK KGNTALHIAA LAGQEDVVRE LVNYGANVNA QSQKGFTPLY
MAAQENHLEV VKFLLESGAN QNVATEDGFT PLAVALQQGH ENVVAHLINY GTKGKVRLPA
LHIAARNDDT RTAAVLLQND PNADVLSKTG FTPLHITAHY ENLNVAQLLL NRGANVNFTP
QNGITPLHVA SRRGNIIMVR LLLDRGAQIE TRTKDELTPL HCAARNGHMR IMEILLDHGA
PIQAKTKNGL SPIHMAAQGD HLDCMRLLLQ YNAEIDDITL DHLTPLHVAA HCGHHRVAKM
LLDKGAKPNA RALNGFTPLH IACKKNHLRV MELLLKTGAS IDAVTESGLT PLHVAAFMGH
LSIVKILLQR GASPNVSNVK VETPLHMAAR AGHTDVAKYL LQNKAKVNAK AKDDQTPLHC
AARIGHTSMV KLLLENNANP NLATTAGHTP LHITAREGHV DTSLALLDKE ASQACMTKVG
WCSLCSQPRQ GFPGGAEVGL GQAAAGEVPT LLCMALTLCV SPQKGFTPLH NGYTPLHIAA
KQNQLEVARS LLQYGASANA ESMQGVMPLH LAAQEGHADM AGLLISKQAN GNLGNKSGLT
PLHLVAQEGH VPVADVLIRH GVTVDAATRM GYTPLHVASH YGNIKLVKFL LQHQADVNAK
TKLGYTPLHQ AAQQGHTDIV TLLLKHGASP NEVNTNGTTP LAIAKRLGYI SVTDVLKLVT
EETSIPLVSD KHRMSFPETV DEILDVSEDE GEGRRAKLQL IEFVPKLDQV VESPAIPWIP
CVTPETMVVR REDSEQLSKE FDEDSLIPSS PATETSDNIS PVASPVHTGF LVSFMVDARG
GSMRGSRHNG LRVIIPPRTC AAPTRITCRL VKPQKLTTPP PLAEEEGLAS RIITLGPTGA
QFLSPVIVEI PHFASYGRQD RELVVLRSEN GSIWKEHHSR YNESYLDQVL NGMDEELESL
EELEKKRICR IISTDFPLYF VVMSRICQDR DLIGPDGGCL KSTLVPMVQA TFPETAVTKG
VKLALQAQPV PDELVTKLLG NQATFSPIVT VEPRRRKFHR PIGLRIPLPP SWKDNPRDSG
EGDTTSLRLL CSVIGGTGQA QWEDITGTTK LVYANECANF TTNVSARFWL ADCPRTAEAV
HFATVLYEEL KAVPYMAKFV VFAKMNNARE GRLRCYCMTD DKMDKTLEQH ENFREVARSR
DIEVLEGMPL HVELSGNLVP VKKATQQRSF HFQSFQENCL AIPVKVTAAR GFERLGRAGL
WARLCSMPTC VVGTGSKERR RTLTPLALRE RYSILSESTL GMQPALATTP SWALLARELQ
FGVDDINRIR VENPNSLLEQ SVALLNLWVS REGKNAKIEN LYAALRSIDR SEIVDMLEGS
GRQSCSLKGE RHYTDKDYSL SPSQMNGYTS LQDELLSPAS LQYTPPSPLR ADQYWNEVAI
LDAIPMAPTE QDALLELSDM QVWSSGLTPS LVTAEDSSLE CSKAEDSDAV SEGRFLGQLL
DDAHGPDHLG SLDLAEDDTV DSDAMNGLID LLEQEEGQRS EVKLPACERQ AGLAEEQGLE
DEVSFISGQQ RVQTRILESP TVSRVVERSK GRDWNAEGSF VCCLQDLPEG SWQEGVPRSP
CLLPRAAPGA APQGRGQEQV LSEHKGLPVG HWLPALPPHC LALFSPPVLQ GDQVQDIPGE
QVTEEQFTDE QGNIVTKKVS TDQTQSPLSL CPLIGGRMGA YIVKRASLKR GKQ
//
