ID   A0A452Q7I7_URSAM        Unreviewed;       518 AA.
AC   A0A452Q7I7;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Kelch repeat and BTB domain containing 4 {ECO:0000313|Ensembl:ENSUAMP00000000138.1};
GN   Name=KBTBD4 {ECO:0000313|Ensembl:ENSUAMP00000000138.1};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000000138.1, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000000138.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A452Q7I7; -.
DR   STRING; 9643.ENSUAMP00000000138; -.
DR   Ensembl; ENSUAMT00000000174.1; ENSUAMP00000000138.1; ENSUAMG00000000188.1.
DR   GeneTree; ENSGT00940000158775; -.
DR   OMA; RDNMWTE; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   CDD; cd18481; BACK_KBTBD4; 1.
DR   CDD; cd18272; BTB_POZ_KBTBD4; 1.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR042884; KBTBD4.
DR   InterPro; IPR042950; KBTBD4_BACK.
DR   InterPro; IPR042949; KBTBD4_BTB_POZ.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR011498; Kelch_2.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR47195; KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4; 1.
DR   PANTHER; PTHR47195:SF1; KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF07646; Kelch_2; 1.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 2.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF117281; Kelch motif; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022}.
FT   DOMAIN          45..112
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
SQ   SEQUENCE   518 AA;  58083 MW;  AA85ED83D2D85C9F CRC64;
     MESPEEPGAS MDENYFVNYT FKDRSHSGRV AQGIMKLCLE EELFADVTIS VEGREFQLHR
     LVLSAQSCFF RSMFTSNLKE AHNRVIVLQD VSESVFQLLV DYIYHGTVKL RAEELQEIYE
     VSDMYQLTSL FEECSRFLAR TVQVGDCLQV MWLADRHSDP ELYTAAKHCA KAHLAQLQST
     DEFLHLPHHL LTDIISDGVP CSQNPTEAIE AWINFNKEER EVFAESLRTS LKEIGENVHI
     YLIGKESSRT HSLAVSLHCA EDDSISVSGQ NSLCHQITAA CKHGGDLYVV GGSIPRRMWK
     CNNATVDWEW CAPLPRDRLQ HTLVSVPGKD AIYSLGGKTL QDTLSNAVIY YRVGDNVWTE
     TTQLEVAVSG AAGANLNGII YLLGGEENDL DFFTKPSRLI QCFDTETDKC HVKPYVLPFA
     GRMHAAVHKD LVFIVAEGDS LVCYNPLLDS FTRLCLPEAW SSAPSLWKIA SCNGSIYVFR
     DRYKKGDANT YKLDPATSAV TVTRGIKVLL TNLQFVLA
//