ID   A0A452Q9Q1_URSAM        Unreviewed;       270 AA.
AC   A0A452Q9Q1;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=2-aminoethanethiol dioxygenase {ECO:0000313|Ensembl:ENSUAMP00000001102.1};
GN   Name=ADO {ECO:0000313|Ensembl:ENSUAMP00000001102.1};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000001102.1, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000001102.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A452Q9Q1; -.
DR   STRING; 9643.ENSUAMP00000001102; -.
DR   Ensembl; ENSUAMT00000001275.1; ENSUAMP00000001102.1; ENSUAMG00000001057.1.
DR   GeneTree; ENSGT00390000014082; -.
DR   OMA; PQGFPEN; -.
DR   OrthoDB; 2914618at2759; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   GO; GO:0047800; F:cysteamine dioxygenase activity; IEA:Ensembl.
DR   GO; GO:0005506; F:iron ion binding; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   CDD; cd20289; cupin_ADO; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   InterPro; IPR012864; PCO/ADO.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   PANTHER; PTHR22966:SF61; 2-AMINOETHANETHIOL DIOXYGENASE; 1.
DR   PANTHER; PTHR22966; UNCHARACTERIZED; 1.
DR   Pfam; PF07847; PCO_ADO; 1.
DR   SUPFAM; SSF51182; RmlC-like cupins; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022}.
FT   REGION          136..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   270 AA;  29598 MW;  69F62C05F27C0A51 CRC64;
     MPRDNMASLI QRIARQACLT FRGSGGCRSA SDLGAAPGPE APMPQGFPEN LSKLKNLLTQ
     VRAEDLNIAP RKATLQPLSP NLPPVTYMHI YETDGFSLGV FLLKSGTSIP LHDHPGMHGM
     LKVLYGTVRI SCMDKLEAGG GSQPRAPPPE QQFEPPLQAR ERDAVRPGVL RSRAEYTEAS
     GPCVLTPHQD NLHQIDAVDG PAAFLDILAP PYDPDDGRDC HYYRVLEPVR DKEAPGSACD
     LPREVWLLET PQADDFWCEG EPYPGPRVFP
//