ID A0A452QBK3_URSAM Unreviewed; 342 AA.
AC A0A452QBK3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Tetratricopeptide repeat domain 8 {ECO:0000313|Ensembl:ENSUAMP00000001849.1};
GN Name=TTC8 {ECO:0000313|Ensembl:ENSUAMP00000001849.1};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000001849.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000001849.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452QBK3; -.
DR STRING; 9643.ENSUAMP00000001849; -.
DR Ensembl; ENSUAMT00000002115.1; ENSUAMP00000001849.1; ENSUAMG00000001725.1.
DR GeneTree; ENSGT00940000156816; -.
DR OMA; MGRIYIY; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0034464; C:BBSome; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR GO; GO:0060170; C:ciliary membrane; IEA:Ensembl.
DR GO; GO:0061629; F:RNA polymerase II-specific DNA-binding transcription factor binding; IEA:Ensembl.
DR GO; GO:0048560; P:establishment of anatomical structure orientation; IEA:Ensembl.
DR GO; GO:1905515; P:non-motile cilium assembly; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR028796; BBS8.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44177; TETRATRICOPEPTIDE REPEAT PROTEIN 8; 1.
DR PANTHER; PTHR44177:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 8; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF14559; TPR_19; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 258..291
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 342 AA; 39398 MW; F0EA5BECEDA31668 CRC64;
MHVLIGANYT VYFIIYCFCS LFKTKILIQN ELFSKALDLA ALSTEYSQYK DWWWKVQIGK
CYYRLGMYRE AEKQFKSALK QQEMVDTFLY LAKVYISLDQ PVTALNLFKQ GLDKFPGEVT
LLCGIARIYE EMNNISSAAE YYKEVLKQDN THVEAIACIG SNHFYSDQPE IALRFYRRLL
QMGVYNCQLF NNLGLCCFYA QQYDMTLTSF ERALALAENE EEAADVWYNL GHVAVGIGDM
NLAHQCFRLA LVNNNHHAEA YNNLAVLEMR KGHVEQARAL LQTASSLAPH MYEPHFNFAT
VSDKIGDLQR SYIAAQKSEA AFPDHVDTQH LIKQLKQHFA ML
//
