ID   A0A452QJY1_URSAM        Unreviewed;      1299 AA.
AC   A0A452QJY1;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Immunoglobulin like and fibronectin type III domain containing 1 {ECO:0000313|Ensembl:ENSUAMP00000005500.1};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000005500.1, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000005500.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   Ensembl; ENSUAMT00000006247.1; ENSUAMP00000005500.1; ENSUAMG00000004862.1.
DR   GeneTree; ENSGT00940000162073; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   CDD; cd00063; FN3; 4.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 11.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR013098; Ig_I-set.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR040849; MyBP-C_THB.
DR   PANTHER; PTHR13817:SF73; PROTEIN SIDEKICK HOMOLOG; 1.
DR   PANTHER; PTHR13817; TITIN; 1.
DR   Pfam; PF00041; fn3; 4.
DR   Pfam; PF07679; I-set; 5.
DR   Pfam; PF18362; THB; 1.
DR   SMART; SM00060; FN3; 4.
DR   SMART; SM00409; IG; 7.
DR   SMART; SM00408; IGc2; 4.
DR   SUPFAM; SSF49265; Fibronectin type III; 2.
DR   SUPFAM; SSF48726; Immunoglobulin; 6.
DR   PROSITE; PS50853; FN3; 4.
DR   PROSITE; PS50835; IG_LIKE; 4.
DR   PROSITE; PS00290; IG_MHC; 1.
PE   4: Predicted;
KW   Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          29..115
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          447..538
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          645..740
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          745..844
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          846..941
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          945..1037
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          1042..1137
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   DOMAIN          1150..1246
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   REGION          404..455
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        404..424
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1299 AA;  142176 MW;  69CEA70F0D12BD41 CRC64;
     MAGEKRKSAL YGVKILQLVE EIPEGCSTPD FQQKPVALAL QEGKNAIFRA LVCGEPKPKV
     HWQSTKGNLS NSSKYQISSF PGSKEHVLQI NKLTGEDSDL YRCTAVNVYG EATCSTRLLV
     IEVGFRKNRK RHKEPQEGRW KGCQKSWVLG NGAPPPKKKV DMEQVWQLLM TADRKDYERI
     CLKYGIVDYR GMLRKLKEMQ KEREDKMAQY LNAVSNLRHI RVSKEGVATF DLELDLKYAG
     SKIYLYKDGE MVPYGFDNQT KHCLRQLGKR YQFQIRDLQP EDAGIYQVKV EDAEIFSTEL
     DASAIPARVV VPLAEVHCEE QSDAVFECVL SNPCPNATWN FRHRPLQPSN KYEVFVSPDG
     LTHRLVVRGV RFSDMGPYSL GTGFHGSTAW LVVEAGKDKS ILTTSADRHH LGSRRGDLEG
     RSDIYGQGRD ASQSPRSRYK PGTGGFPRET QGPRGHFSQG LADMEVQQGE AVVFSCTLTR
     DLGPVAWFKD GVKLSARDGV VFEQDGLVHR LLIDRVQGTQ AGRYTCVAGH QRSEATLSVH
     DRPVIAPDVA EKLRKPLVVK AGKPVTVKIP FKSHLPVQAV WRKDGAEVGS SSRHGAQVAL
     GDDFTRLCLP SAGRKDGGQY SVTLKSEGGS VQAELTLQVI DKPQAPQGPL EVQNRQGAGV
     CLCWRPPKDD GGRAVEHYVV ERQQAGRSAW LRAGQAPADS TTFTDADVEQ GKKYTFRVRA
     VTSEGAGEAL ESTEVLVAPE ALPGPPSSPT IQSASSQGIT LTWTAPRGPG SAHILGYLIE
     KRKKGSNTWM AVNVQPVPER RWTVVDVRQG CQYEFRVTAV SPSGPGEPGP PSDAVFARDP
     MRPPGPVRDL QVIDTSHTSI TLSWAQPDAQ DGDRAQGYVV ELRGSDSLQW SPCHEGTVPV
     TTFTAKGLRP QESYFVRVTA VNDGGRGQPT ALDTLVQVMP VAVRPKFLMD SSTRDSLMVR
     VGDTIRVPVY FEAVPMPEVT WLKDGLPLLR SNVTSTKDGL TQLLIPVASL SDSGLYTVVL
     RSLQGGEVAY RFSLRVAACP KAPGPIRLQE NVPGTVTAEW EPSPDEAGDI PLYYEVLTRS
     SAHGPWRQAA DRVHTNHFTL LGVLPGHEYH FRVVAKNELG ASLPSDTSQP WCISRQRDKF
     TVKAPSYREP NLSQKPRFLV GLRPHLLPQG CECCMSCAVQ GWPRPHVTWF KDEQSLAGNP
     AVYSTDLLGV CSLIIPSVSP KDSGLYKAVA ENALGQAVSM ASLIVTGKRA ALAEGGREGE
     SEAQPPTCLG GALPVPSERV AGLGVRVQGR LTAVSTGTP
//