ID A0A452QP47_URSAM Unreviewed; 564 AA.
AC A0A452QP47;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Staphylococcal nuclease domain-containing protein 1 {ECO:0000256|ARBA:ARBA00017230};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000007213.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000007213.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452QP47; -.
DR STRING; 9643.ENSUAMP00000007213; -.
DR Ensembl; ENSUAMT00000008170.1; ENSUAMP00000007213.1; ENSUAMG00000005604.1.
DR GeneTree; ENSGT00510000047270; -.
DR OMA; DWIPDAH; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR CDD; cd00175; SNc; 1.
DR CDD; cd20433; Tudor_TDRD11; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.40.50.90; -; 3.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR016071; Staphylococal_nuclease_OB-fold.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047386; Tudor_TDRD11.
DR PANTHER; PTHR12302; EBNA2 BINDING PROTEIN P100; 1.
DR PANTHER; PTHR12302:SF28; STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00565; SNase; 3.
DR Pfam; PF00567; TUDOR; 1.
DR SMART; SM00318; SNc; 2.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF50199; Staphylococcal nuclease; 3.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50830; TNASE_3; 2.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 37..150
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 179..314
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 383..441
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
SQ SEQUENCE 564 AA; 63554 MW; 7695A79562553870 CRC64;
MHSIPQLPLR DFKGFYVPGN LEELLLFCGF LGTSNISLDK NKKLRPLYDI PYMFEAREFL
RKKLIGKKVN VTVDYIRPAS PATETVPAFS ERTCATVTIG GINIAEALVS KGLATVIRYR
QDDDQRSSHY DELLAAEARA IKNGKGLHSK KEVPIHRVAD ISGDTQKAKQ FLPFLQRAGR
SEAVVEYVFS GSRLKLYLPK ETCLITFLLA GIECPRGARN LPGLVQEGEP FSEEATLFTK
ELVLQREVEV EVESMDKAGN FIGWLHIDSA NLSVLLVEHA LSKVHFTAER SSYYKSLLSA
EEAAKQKKEK VWAHYEEQPV EEVAPVLEEK ERSASYKPVF VTEITDDLHF YVQDVETGTQ
LEKLMENMRN DIASHPPVEG SYAPRRGEFC IAKFVDGEWY RARVEKVESP AKVHVFYIDY
GNREILPSSR LGTLPPAFST RVLPAQATEY AFAFIQVPQD EDARTDAVDS VVRDIQNTQC
LLNVEHLSAG CPHVTLQFAD SKGDVGLGLV KEGLVMVEVR KEKQFQKVIT EYLNAQESAK
SARLNLWRYG DFRADDADEF GYSR
//
