ID   A0A452QQ55_URSAM        Unreviewed;       593 AA.
AC   A0A452QQ55;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=GATA zinc finger domain containing 2B {ECO:0000313|Ensembl:ENSUAMP00000007652.1};
GN   Name=GATAD2B {ECO:0000313|Ensembl:ENSUAMP00000007652.1};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000007652.1, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000007652.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A452QQ55; -.
DR   STRING; 9643.ENSUAMP00000007652; -.
DR   Ensembl; ENSUAMT00000008641.1; ENSUAMP00000007652.1; ENSUAMG00000006600.1.
DR   GeneTree; ENSGT00390000004097; -.
DR   OMA; VHGMGWD; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   GO; GO:0000781; C:chromosome, telomeric region; IEA:Ensembl.
DR   GO; GO:0016581; C:NuRD complex; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 6.10.250.1650; -; 1.
DR   Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR   InterPro; IPR040386; P66.
DR   InterPro; IPR032346; P66_CC.
DR   InterPro; IPR000679; Znf_GATA.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   PANTHER; PTHR13455:SF4; TRANSCRIPTIONAL REPRESSOR P66-BETA; 1.
DR   PANTHER; PTHR13455; TRANSCRIPTIONAL REPRESSOR P66-RELATED; 1.
DR   Pfam; PF00320; GATA; 1.
DR   Pfam; PF16563; P66_CC; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR   PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00094}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00094};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00094}.
FT   DOMAIN          414..444
FT                   /note="GATA-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50114"
FT   REGION          62..142
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          211..246
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          159..186
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        79..118
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   593 AA;  65050 MW;  4463A83905C9591A CRC64;
     MDRMTEDALR LNLLKRSLDP ADERDDVLAK RLKMEGHEAM ERLKMLALLK RKDLANLEVP
     HELPTKQDGS GVKGYEEKLN GTLRPHGDNR TAGRPGKENI SDEPVDMSAR RSEPDRGRLT
     PSPDIIVLSD NEASSPRSSS RMEERLKAAN LEMFKGKGME ERQQLIKQLR DELRLEEARL
     VLLKKLRQSQ LQKENVVQKT PVVQNAASIV QPSPAHGGQQ GLSKLPSRPG AQGVEPQSLR
     TLQGHSVIRS ATNTTLPHML MSQRVIAPNP AQLQGQRGPP KPGLVRTTTP NMNPAINYQP
     QSSSSVPCQR TASSAIYMNL ASHIQPGAVN RVSSPLPSPS AMTDAANSQA AAKLALRKQL
     EKTLLEIPPP KPPAPLLHFL PSAANSEFIY MVGLEEVVQS VIDSQGKSCA SLLRVEPFVC
     AQCRTDFTPH WKQEKNGKIL CEQCMTSNQK KALKAEHTNR LKNAFVKALQ QEQEIEQRLQ
     QQAALSPTAA PAVSSVSKQD TIMRHHTLRQ APQPQSSLQR GIPTSARSML SNFAQAPQLS
     VPGGLLGMPG VNIAYLNTGI GGHKAPSLAD RQREYLLDMI PPRSIAQSIS GQK
//