GenomeNet

Database: UniProt
Entry: A0A452QS03_URSAM
LinkDB: A0A452QS03_URSAM
Original site: A0A452QS03_URSAM 
ID   A0A452QS03_URSAM        Unreviewed;      2990 AA.
AC   A0A452QS03;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   10-FEB-2021, entry version 10.
DE   SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSUAMP00000008345};
GN   Name=CENPF {ECO:0000313|Ensembl:ENSUAMP00000008345};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000008345, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Ensembl:ENSUAMP00000008345, ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000008345}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   Ensembl; ENSUAMT00000009412; ENSUAMP00000008345; ENSUAMG00000007040.
DR   GeneTree; ENSGT00730000111187; -.
DR   OMA; YNAQLVQ; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 3.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022}.
FT   DOMAIN          1..302
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1884..2024
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2120..2259
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2302..2441
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2846..2889
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          237..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1662..1682
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2792..2990
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          159..186
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          268..372
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          381..433
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          458..482
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          504..610
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          618..638
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          646..666
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          681..708
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          720..754
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          834..861
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          894..942
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          950..991
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1024..1072
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1113..1154
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1197..1238
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1288..1315
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1392..1412
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1545..1608
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1781..1843
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1881..1901
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1923..1950
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1958..1988
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2005..2074
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2131..2193
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2201..2267
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2285..2305
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2313..2449
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2492..2592
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2600..2701
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2710..2740
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2748..2768
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        241..268
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2792..2808
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2831..2860
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2900..2956
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2990 AA;  343005 MW;  6BE65DEA497B141B CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LETLEAALQK QKQKVENEKT
     EGANLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
     CKSELERSQQ AAQAADVSVY SSSTPQKIFA TPLTPSSKYE DLKEKYNKEV EERKRLEAEV
     KALQAKKASQ AIPQSTMNHR DIARHQASSS VFSWQQEKTP TRLSLNALKT PIRRDFSASH
     FSGEQEVTPS GSTLQTGKRD ANSSFCDNSS NSHLLDQLKA QNQELRNKIS DLELHLQGQE
     KEMKGQANKC QELQLQLEKA KAELIEKEKA LNKSRDELVR STAQYDQASA KCTALEQKLK
     RLSEDLSCQR QNAESARCSL EQKLKEKEKE FQEELSRQQR TFQALDQECA QMKARLTQEL
     QQAKNTHNIL QADLDKVTSG KYQLEKTLEE FKQKFCRAEQ ALQASQVKEN ELRRSSEEAK
     KEYSLLKGQS EQRAREVCHL EEELRKAKQS LSQSQNVAEE MRAKNASQET MLRDLQEKVN
     QQENSLTLDK LKLALVDLEK QRDCSQDLLK KREHHIEQLN DKLSKMEKES EALLIALELK
     KKEYEELKEE KTLFARWKSE NEQLLSQLES EKGSLQSKIN HLETCLKTQQ IKSHEYNEKV
     RTLEMESENL HVEIRNLHNM IDSKTVEVET QKQAYADLQQ KAEFSDQKHK KETENMCLKI
     SELTGQVEDL EHKLQLLSSE VIDKDQRYQD LQAEYESLGD LLKSKDSSLV TNEAHHRSLL
     AFEQQSAMNN SFVNIIGEQG STPSERSKCH LEALPSPKSS AILQNRVLSL EFSLESQKQM
     NSDLQKQCEE LVQIRGEIEE NLIKAEQMHQ SFVAETSQRI SKLQEDTSVH QNAFAETLVA
     LENKEREIQL LNEKLETEQA EIQELKKSNH LLQESLKALQ LLSETLSSEK KEMSSTISLN
     RKEIEDLTQE NETLKEINAT LNQEKINLLQ KSESFSNCID ERDKSISELS NQYKQERLIL
     QQRCEETGRA FEDLSEKYQA AQEKNSQLEC LLNECTSACE NRQKELDHLK ETFAREQEVF
     VTKLALAEET NQNLVLELGA VQQDLRSEIA DIQNNSKSEA DGLKQEIMTL KEEHSKMQKE
     LNALMQENEH LMMLMETKQE HQILESEAIS DSVEGESEIN KCHVQLPMDL EVKDPSLDCY
     NAQLMQLEAK RRNRELKLQE SEKDKERLQH ELQTIGIELE TGNLQRDAQS QELSGPKDCD
     IGTEEKYISV LHELSASQND NVLLQCSLQT AMSKLSELEK MCEMLQVEKL ELMSELNDSR
     SECITTTSKM AEEMEKLVNE VKIPNDENDL LQGELVKDMV EGESDERQNE QKRASFNPLD
     DSNCYEHLTL SNKEVQMHFA ELQEKFSSLQ SEHKVLYDQH RQVSSKMSEL QSYVDTLKAE
     NSILSTSLRN FQGDLVKEEM LGPEEGHFLS LSFSCVTDSP SLTRLGESSF CKDLLDQTGE
     TSLLNNLEGT ISANQSNIEE GSCCSPGEEK NLTRKEILSA PARSVEELET LCQMYLESLK
     KLEDKIESQE IMKNKEIKEL EQLLSSEREE LDCLRKQYLS ENEQWQQKLT SVTMEMESKL
     AAEKKQTEHL SFELEVARLQ LQGLDLSSRS LLGPDIEEVG NNSCDVKESE EHTLETKERT
     PKHDIHQICE EGVQQDLNLE MEKVTKTSPV RFTEEWSREQ SLETPAEDKT EGCLERISDL
     SFSGPNALVP MDFLETQVTI QNLQLQVKES SNEHLRLLHI IEERDKKVES LLNEIKELDS
     KLHVQKAQIT AKMEACIELE KMVEELKKEK SNLSERLESF SCDKQKLHQR TESLEGLNSS
     LEICADKLSH AIIEDSVAKV NDNWRERFLD VENELKRIQS EKGSIEHHAL SLEADLETVQ
     TEKLYLEKDN ENQQNVIIRL EEELSVVTSE RNRLHGELDT LSKENKELDL MSEKMKQKIR
     ELESHQGEGH IDVAGAEVRD QTQLIETLSS DVTKLLEENT HLQEQLQNVE KDSQALSLVK
     SELEIQIEQL SREKESLARE SESLQTRLHE SEHEKLTVTK ALEGALLEKG EVAVRLSSTQ
     EEVYQLRQGI EKLRVRIEAD DKKQLHVLEK LRTSERKADS LQDKVENLER ELQMSEENQE
     LVILDAESSK AEVEALKTQM ELMTKSLRDL ELDLGTIRFE KENLVKQLQE KQGQVSELDT
     LLSSLKGRLE EEEQEKIEMR EESKAALEML QTQLKELNEE VIALCHDQEI QKVEEQSLDP
     SVQEIHQLRN SIEKLKARLE ADEKEQLQVL GKLTESEHHV DLLKDRVENL ERELERSREN
     QERVILEAEN SKAEVGTLKA KIEEMAQTLR DLELDLVHIR SEKENVIKEL QKEQGRVSEL
     EILNSSFENL LQEKEQEKVQ MKEESKIAVE TLQTQLKELN EKVAALCHDQ DTWKAQAQSL
     RSQVDALGYE KAQLLQGLDE VKNNYLNVQS SANGLLQQVE DGKQKLEKKD EEISILKNQV
     QDREQLASKL SQVEGEQQLW KKQKVELENL MVELEEKIRV LQSKNDTLQD TLEALQDSHR
     DLEKELELTK MENVSFVEKV NAMTGKETEL QREMREMAQK TTELKEEYFG EKNRLTEELN
     IMSQEIKSSK ADNVKYTNQL KKENERAQGK IKLLIKSCKQ LEEEKEMLQK ELSHLEAAQE
     KQKTGSTVVD SNVEDLMAEI KELKETLEEK NKEADEYLDK YCSLLISHEK LEKAKEMLET
     QVARLSSQSK LNLQHSPLLN SVVPEAFSAP SATEKKLSSS QSKASGKRQR STGIREDGGG
     TAPSTPETFS KKSRKAVKSG IHPAEDARDT EFEPEGLPEV VKKGFADIPT GKASPYVLRR
     TTMPTRTSPR LAAQKLAPSP LSLNKENHAE TSQPTAGGSR SQKVKVAQQS PADSSAPFRE
     PTTRSLSVSN LPERSPANSP REGLRAKRGR LAPSPEAVPE SKSSENCRVQ
//
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