ID A0A452QSI8_URSAM Unreviewed; 725 AA.
AC A0A452QSI8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Kazrin, periplakin interacting protein {ECO:0000313|Ensembl:ENSUAMP00000008517.1};
GN Name=KAZN {ECO:0000313|Ensembl:ENSUAMP00000008517.1};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000008517.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000008517.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452QSI8; -.
DR STRING; 9643.ENSUAMP00000008517; -.
DR Ensembl; ENSUAMT00000009602.1; ENSUAMP00000008517.1; ENSUAMG00000007169.1.
DR GeneTree; ENSGT00940000154570; -.
DR OMA; RNEDCFD; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0001533; C:cornified envelope; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0030057; C:desmosome; IEA:Ensembl.
DR GO; GO:0016607; C:nuclear speck; IEA:Ensembl.
DR CDD; cd09564; SAM_kazrin_repeat1; 1.
DR CDD; cd09567; SAM_kazrin_repeat2; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR037614; Kazrin.
DR InterPro; IPR037613; Kazrin_SAM_rpt_1.
DR InterPro; IPR037615; Kazrin_SAM_rpt_2.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12776:SF1; KAZRIN; 1.
DR PANTHER; PTHR12776; KAZRIN-RELATED; 1.
DR Pfam; PF00536; SAM_1; 2.
DR SMART; SM00454; SAM; 2.
DR SUPFAM; SSF47769; SAM/Pointed domain; 2.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000291022}.
FT DOMAIN 404..469
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 490..546
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 685..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 33..211
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..322
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..710
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 725 AA; 81377 MW; B477EE73C4E0B4F5 CRC64;
VRGAGHSEGK GPEAEKTSRS QRPLPLTVCP SPLVLLREEV SRLQEEVHLL RQMKEMLTKD
LEESQGGKSS EVLSATELRV QLAQKEQELA RAKEALQAMK ADRKRLKGEK TDLVSQMQQL
YATLESREEQ LRDFIRNYEQ HRKESEDAVK ALAKEKDLLE REKWELRRQA KEATDHATAL
RSQLDLKDNR MKELEAELAM AKQSLATLTK DVPKRHSLAM PGETVLNGNQ EWVVQADLPL
TAAIRQSQQT LYHSHPPHPA DRQAVRVSPC HSRQPSVISD ASAAEGDRSS TPSDINSPRH
RTHSLCNGDS PGPVQKNLHN PIVQSLEDLE DQKRKKKKEK MGFGSISRVF ARGKQRKSLD
PGLFDDSDSQ CSPTRQSLSL SEGEEQMDRL QQVELVRTTP MSHWKAGTVQ AWLEVVMAMP
MYVKACAENV KSGKVLLSLS DEDLELGLGV CSSLHRRKLR LAIEDYRDAE AGRSLSKAAD
LDHHWVAKAW LNDIGLSQYS QAFQNHLVDG RMLHSLMKRD LEKHLNVSKK FHQVSILLGI
ELLYQVNFSR EALQERRARC ETQNIDPVVW TNQRVLKWEY ADNLTNSGIH GAVLVLEPTF
NAEAMATALG IPSGKHILRR HLAEEMSAIF HPANSSGIRE AERFGTPPGR ASSITRAGKE
ENSGGIKYKA GRLPLGKIGR GFSKDPDFHD DYGSLQNEDC GDDDPQGRPE QCRLEGYNGL
EVTNV
//
