ID   A0A452QXI8_URSAM        Unreviewed;       825 AA.
AC   A0A452QXI8;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=GTF2I repeat domain containing 1 {ECO:0000313|Ensembl:ENSUAMP00000010544.1};
GN   Name=GTF2IRD1 {ECO:0000313|Ensembl:ENSUAMP00000010544.1};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000010544.1, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000010544.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A452QXI8; -.
DR   Ensembl; ENSUAMT00000011846.1; ENSUAMP00000010544.1; ENSUAMG00000008608.1.
DR   GeneTree; ENSGT00940000159414; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1460.10; GTF2I-like; 4.
DR   InterPro; IPR004212; GTF2I.
DR   InterPro; IPR036647; GTF2I-like_rpt_sf.
DR   PANTHER; PTHR46304; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR46304:SF1; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF02946; GTF2I; 4.
DR   SUPFAM; SSF117773; GTF2I-like repeat; 4.
DR   PROSITE; PS51139; GTF2I; 4.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   REGION          70..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          203..223
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          241..289
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          440..466
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          481..531
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          766..825
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        514..531
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   825 AA;  90858 MW;  1F74B8EAAE4B444D CRC64;
     SHPQNCHWRC PQRGGTSLSK LNAEVACVAV HDESAFVVGT EKGRMFLNAR KELQSDFLRF
     CRGAPWKEPE AEHPKKVSRG EGGGRSVPRS SLEHGSDVYL LRKMVDELFD VLYSEALGRA
     SVVPLPYERL LREPGLLAVQ GLPEGLAFRR PVDYDPKALM AILEHSHRIR FKLKRPLEDG
     GRDSKALVEL NGVSLIAKGS RDCGLHGQAP KGPPQDLPPT ATSSSVASFL YSTALPNHTT
     RELKQEAPAC PLAPSDLGLG RPGPEPKASG AQDFPDCCGQ KPPGPGGPLI QNVHASKRIL
     FSIVHDKSEK WDAFIKETED INTLRECVQI LFNSRYAEAL GLDHMVPVPY RKIACDPEAV
     EIVGIPDKIP FKRPCTYGVP KLKRILEERH SIHFIIKRMF DERIFTGNKF TKDPTKLEPA
     SPPEDTSAEI SRAAVLDLPG TARSDKNGVS EDCGPGTSGE LSGLRPIKME PEDLDIIQVT
     VPDPSPTSEE MTDSMPGHLP SEDSGYGMEM LTEKGPSEDP RPEERPVEDS HGDVIRPLRK
     QVELLFNTRY AKAIGISEPV KVPYSKFLMY PEELFVVGLP EGISLRRPNC FGIAKLRKIL
     EASNSIQFVI KRPELLTEGV KEPITDSQEN YDARLSRIDI ANTLREQVQD LFNKKYGEAL
     GIKYPVQVPY KRIKSNPGSV IIEGLPPGIP FRKPCTFGSQ NLERILAVAD KIKFTVTRPF
     QGLIPKPGKR HWLWGGRLAW EAGCSAGGRR PEPSLLWDAR PCPTVLPPPL GTGPRWEEVT
     VEPRAEKKGW GGGTGDSRAQ PGQGSGRRGR AGSLPSTPDE GAWLT
//