ID A0A452R1V2_URSAM Unreviewed; 468 AA.
AC A0A452R1V2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=DENN domain containing 2D {ECO:0000313|Ensembl:ENSUAMP00000012224.1};
GN Name=DENND2D {ECO:0000313|Ensembl:ENSUAMP00000012224.1};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000012224.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000012224.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452R1V2; -.
DR Ensembl; ENSUAMT00000013739.1; ENSUAMP00000012224.1; ENSUAMG00000009873.1.
DR GeneTree; ENSGT00950000182931; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.200; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR PANTHER; PTHR15288; DENN DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR15288:SF2; DENN DOMAIN-CONTAINING PROTEIN 2D; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00800; uDENN; 1.
DR PROSITE; PS50211; DENN; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000291022}.
FT DOMAIN 52..442
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
SQ SEQUENCE 468 AA; 53004 MW; 967077F6A00BEFA4 CRC64;
LTQQGKKDRW ALDPGVLVSG SLQDNLRDTG KEPERAQEHC LPAFAGGQHF FEYLLVVSLK
KKSAGADYEP TITYQFPKRE NLLRGQQEEE ERLLGAIPLF CFPDGNEWAP LTEYPRETFS
FVLTNVDGSR KIGYCRRLLP AGRGPRLPKV YCIISCLGCF GLFSKILDEV EKRHQISLAV
IYPFMQGLRE AAFPAPGKTV TLKSFIPDSG TEFISLTRPL DSHLEHVDFS SLLRCLRFEQ
ILQIFASAVL ERRIIFLAEG LSTLSQCIHA AAALLYPFSW AHTYIPVVPE SLLDTVCCPT
PFMVGVQTRF QQQVMDSPME EVLLVNLCEG TFLMSVGDEK DILPPKLQDD ILDSLGQGTN
EPQTSEQLNE HVSGPFVQFF VKTVGHYASY IKREANGQGH FQERAFCKAL TSKANRRFVK
KFVKTQLFSL FIQEAEKSRN PPAGYFQQKI LEYEDQKKQK KSREKTVK
//
