ID A0A452R727_URSAM Unreviewed; 1138 AA.
AC A0A452R727;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Zinc finger and AT-hook domain containing {ECO:0000313|Ensembl:ENSUAMP00000014365.1};
GN Name=ZFAT {ECO:0000313|Ensembl:ENSUAMP00000014365.1};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000014365.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000014365.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452R727; -.
DR Ensembl; ENSUAMT00000016121.1; ENSUAMP00000014365.1; ENSUAMG00000011329.1.
DR GeneTree; ENSGT00940000156658; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 11.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24403; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24403:SF66; ZINC FINGER PROTEIN 513; 1.
DR Pfam; PF00096; zf-C2H2; 4.
DR Pfam; PF13909; zf-H2C2_5; 1.
DR SMART; SM00355; ZnF_C2H2; 17.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 7.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 12.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 168..195
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 196..223
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 251..279
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 301..328
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 329..351
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 355..383
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 637..664
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 725..748
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 804..831
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 832..859
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 861..888
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 889..917
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 56..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 499..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..80
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..451
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1138 AA; 126833 MW; FCBE6CE64FF227EB CRC64;
LTAAVSRGST LPGSGSFRMA PRIVHPSLPP IILRYFIHLG IICSVGDESD LELERKYKED
DREKTPRRPR TQRTEKVQKI PSGKEAGQIS GVKKPIISVV LTAHEAIPGA TKIVPVEAGP
PETGTANPEA TTADLAPRRG YQEYAIQQTP YEQPMKSSRL GPTQLKIFTC EYCNKVFKFK
HSLQAHLRIH TNEKPYKCPQ CSYASAIKAN LNVHLRKHTG EKFACDCCSF TCLSKGHLKV
HVERVHKKIK QHCRFCKKKY SDVKNLIKHI RDAHDPQDKK VKEALDELCL MTREGKRQLL
YDCHICERKF KNELDRDRHM LVHGDKWPFA CELCGHGATK YQALELHVRK HPFVYVCAVC
LKKFVSSIRL RSHIREVHGA AQEPGVFTSS INQSFCLLEP GGDIQQEALG GQLQLAEEEF
VFQGVNAPKE AACPRDAQPE GGRKETEASV DEPAPPAHLA APQAESTVLP PCELEAAVDS
SDLRSHSVVS DEFLLKNDTS SAGARTAPEE TLDAPHRASS QTQGKEVTPL LSEARRAETS
QDTEGAESPP GAGQEVAAPP SEGPDPGRCL RSNPGEASDP ALVTGGGDLA LPQPDSCTPA
SEHRAGISAF MKILDGLQKR RMNTGLCERI RKVYGDLECE YCGKLFWYQV HFDMHVRTHT
REHLYHCSQC HYSSITKNCL KRHVIQKHSN ILLKCPTDGC DYNTPDKYKL QAHLKVHTEL
DKRSYSCPVC EKSFSEDRLI KSHIKTNHPE VSMSTISEVL GRRVQLKGLI GKRAMKCPYC
DFYFMKNGSD LQRHIWAHEG VKPFKCSLCE YATRSKSNLK AHMNRHSTEK THLCDMCGKK
FKSKGTLKSH KLLHTADGKQ FKCTVCDYTA AQKPQLLRHM EQHASFKPFR CAHCHYSCNI
SGSLKRHYNR KHPNEEYANV GTGELAADAL VQQGGLKCPV CSFVYGTKWE FNRHLKNKHG
LKLVENEGDS KWEPATETPE EPSTQYVHIT ETEEDVQGTQ AAVAALQDLR YTSESGDRLD
PTAVNILQQI IELGTEAHDA TAVASVVAMA PGTVTVVKQV TDEEPSSNHT VMIQETLQQA
SVELAEQHHL VVSSDDVEGI ETVTVYTQGG EASEFIVYVQ EAMQPMEEQA VGPQAQEL
//
