ID A0A452R7Q1_URSAM Unreviewed; 511 AA.
AC A0A452R7Q1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Tigger transposable element derived 4 {ECO:0000313|Ensembl:ENSUAMP00000014401.1};
GN Name=TIGD4 {ECO:0000313|Ensembl:ENSUAMP00000014401.1};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000014401.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000014401.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00320}.
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DR AlphaFoldDB; A0A452R7Q1; -.
DR STRING; 9643.ENSUAMP00000014401; -.
DR Ensembl; ENSUAMT00000016160.1; ENSUAMP00000014401.1; ENSUAMG00000011571.1.
DR GeneTree; ENSGT00940000160195; -.
DR OMA; QWMQKLD; -.
DR OrthoDB; 2382272at2759; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR InterPro; IPR007889; HTH_Psq.
DR PANTHER; PTHR19303:SF18; TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4; 1.
DR PANTHER; PTHR19303; TRANSPOSON; 1.
DR Pfam; PF04218; CENP-B_N; 1.
DR Pfam; PF03184; DDE_1; 1.
DR Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR SMART; SM00674; CENPB; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51253; HTH_CENPB; 1.
DR PROSITE; PS50960; HTH_PSQ; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Reference proteome {ECO:0000313|Proteomes:UP000291022}.
FT DOMAIN 12..63
FT /note="HTH psq-type"
FT /evidence="ECO:0000259|PROSITE:PS50960"
FT DOMAIN 75..146
FT /note="HTH CENPB-type"
FT /evidence="ECO:0000259|PROSITE:PS51253"
FT DNA_BIND 39..59
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00320"
FT REGION 433..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..451
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 511 AA; 57555 MW; 320FC0FFECA37510 CRC64;
MAEASEDASA LPVTVKKKKS LSIEEKIDII NAVESGKKKA EIAAEYGIKK NSLSSIMKNK
DKVLEAFESL RFDPKRKRLR TAFYTDLEEA LMRWYRIAQC LNVPVNGPML RLKANDFAQK
LGHNDFKCSN GWLDRFKSRY GLVFRAQPVE ATGVSVDPST VWHQNVLPYY LNDYHPKNVF
NIKETGLLYR MLPTNTFAFK GETCSIGKLC KDRITLVVGT NMDGSEKLPL LIIGKNRNPH
CFKGIKSLPV CYEANRMAWM TSDVFEQWMR KLDEKFQAQQ RRVVIFVDSF PSHPEVKDLK
SIELAFFPSC LSSKFIAMKQ GVIKSLKIKY RHCLIKKFLS SVEGSKEFTF SLLDAVDTLH
LCWRAVTPET IIKSYEEAGF KSQKGESDKT NAETDTGLDL VAYAQAAGVE FPEGLSIEEY
ASLDDDLETC EAAPEGDSVC TEERKSDDTG FYASDEEDDG GSLGTELPLP SKNEAITALD
TLKNFLRSQD MNDELHNSLA DLEIFINSSS K
//
