ID A0A452R9U3_URSAM Unreviewed; 759 AA.
AC A0A452R9U3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Kirre like nephrin family adhesion molecule 1 {ECO:0000313|Ensembl:ENSUAMP00000015374.1};
GN Name=KIRREL1 {ECO:0000313|Ensembl:ENSUAMP00000015374.1};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000015374.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000015374.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily.
CC {ECO:0000256|ARBA:ARBA00008637}.
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DR AlphaFoldDB; A0A452R9U3; -.
DR Ensembl; ENSUAMT00000017232.1; ENSUAMP00000015374.1; ENSUAMG00000012280.1.
DR GeneTree; ENSGT00940000155795; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR CDD; cd00096; Ig; 1.
DR CDD; cd05759; IgI_2_KIRREL3-like; 1.
DR CDD; cd05898; IgI_5_KIRREL3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF14; KIN OF IRRE-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000291022}.
FT DOMAIN 36..134
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 139..235
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 242..318
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 327..392
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 411..507
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 657..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 759 AA; 82780 MW; 39BEE5F3A6217938 CRC64;
KHRGPPATNS PPGHSSLLPR PLPSCMSLPN AGLALPGTQT RFSQEPADQT VVAGQRAVLP
CVLVNYSGIV QWTKDGLALG MGQGLKAWPR YRVVGSADAG QYNLEITDAE LSDDASYECQ
ATEAALRSRR AKLTVLIPPE DTRIDGGPVI LLQAGTPHNL TCRAFNAKPA ATIIWFRDGT
QQEGAVASTE LLKDGKRETT ISQLLINPTD LDIGRVFTCR SVNEAIPTGK ETSIELDVHH
PPTVTLSIEP QTVQEGERVV FTCQATANPE ILGYRWAKGG FLIEDAHESR YETNVDYSFF
TEPVSCEVHN RVGSTNVSTL VNVHFAPRIV VDPKPTTTDI GSDVTLTCVW VGNPPLTLTW
TKKDSNMVLS NSNQLLLKSV SQADAGTYTC RAIVPRIGVA EREVPLYVNG PPIISSEAVQ
YAVRGDGGKV ECFIGSTPPP DRIAWAWKEN FLEVGTLERY TVERTNSGSG VLSTLTISNV
VEADFQTHYN CTAWNSFGPG TAIIQLEERE VLPVGIIAGA TIGAGYGPRR KDVTLRKLDI
KVETVNREPL TMHSDREDDT ASVSTATRVM KAIYSSFKDD VDLKQDLRCD AMDTREEYEM
KDPTNGYYNV RAHEDRPASR AVLYADYRAP GPARFDGRPA SRLSHSSGYA QLSTYSRAPA
SDFGPEPAAP GPATPAGADS AGTLSYENYD KFNPHPFPAA AGYPTYRLGY PQAPPSGLER
TPFEAYDPIG KYATATRFSY TSQHSDYGQR FQQRMQTHV
//
