ID   A0A452RJ55_URSAM        Unreviewed;       577 AA.
AC   A0A452RJ55;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=MSL complex subunit 2 {ECO:0000313|Ensembl:ENSUAMP00000019031.1};
GN   Name=MSL2 {ECO:0000313|Ensembl:ENSUAMP00000019031.1};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000019031.1, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000019031.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A452RJ55; -.
DR   STRING; 9643.ENSUAMP00000019031; -.
DR   Ensembl; ENSUAMT00000021281.1; ENSUAMP00000019031.1; ENSUAMG00000015047.1.
DR   GeneTree; ENSGT00390000016814; -.
DR   OMA; TEVCDSN; -.
DR   OrthoDB; 4153116at2759; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   GO; GO:0072487; C:MSL complex; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   CDD; cd13122; MSL2_CXC; 1.
DR   CDD; cd16522; RING-HC_MSL2; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR037922; MSL2.
DR   InterPro; IPR032049; Msl2-CXC.
DR   InterPro; IPR032043; Msl2_Znf-RING.
DR   InterPro; IPR033467; Tesmin/TSO1-like_CXC.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR16048:SF3; E3 UBIQUITIN-PROTEIN LIGASE MSL2; 1.
DR   PANTHER; PTHR16048; MSL2-RELATED; 1.
DR   Pfam; PF16682; MSL2-CXC; 1.
DR   Pfam; PF16685; zf-RING_10; 1.
DR   SMART; SM01114; CXC; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022}.
FT   DOMAIN          457..504
FT                   /note="Tesmin/TSO1-like CXC"
FT                   /evidence="ECO:0000259|SMART:SM01114"
FT   REGION          405..428
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        411..425
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   577 AA;  62504 MW;  ABDE3836396F1EAF CRC64;
     MNPVNATALY ISASRLVLNY DPGDPKAFTE INRLLPYFRQ SLSCCVCGHL LQDPIAPTNS
     TCQHYVCKPC KGKKMMMKPS CSWCKDYEQF EENKQLSILV NCYKKLCEYI TQTTLARDII
     EAVDCSSDIL ALLNDGSLFC EETEKPSDSS FTLCLTHSPL PSTSEPTADP QASLSPISES
     TLSIAIGSSV INGLPTYNGL SIDRFGINIP SPEHSNTIDV CNTVDIKTED LSDSLPPVCD
     TVATDLCSTG IDICSFSEDI KPGDSLLLSV EEVLRSLETV SNTEVCCPNL QPNLEATVSN
     GPFLQLSSQS LSHNVFMSTS PALHGLSCTA ATPKVAKLNR KRSRSESDSE KVQPLPISTI
     IRGPTLGASA PVTVKRESKI SLQPIATVPN GGTTPKISKT VLLSTKSMKK SHEHGSKKSH
     SKTKPGILKK DKTVKEKIPS HHFMPGSPTK TVYKKPQEKK GCKCGRATQN PSVLTCRGQR
     CPCYSNRKAC LDCICRGCQN SYMANGEKKL EAFAVPEKAL EQTRLTLGIN VTSIAVRNAS
     TSTSVINVTG SPVTTFLAAS THDDKSLDEA IDMRFDC
//