ID   A0A452RJR6_URSAM        Unreviewed;       386 AA.
AC   A0A452RJR6;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Spindlin interactor and repressor of chromatin binding {ECO:0000313|Ensembl:ENSUAMP00000019311.1};
GN   Name=SPINDOC {ECO:0000313|Ensembl:ENSUAMP00000019311.1};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000019311.1, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000019311.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A452RJR6; -.
DR   STRING; 9643.ENSUAMP00000019311; -.
DR   Ensembl; ENSUAMT00000021595.1; ENSUAMP00000019311.1; ENSUAMG00000015259.1.
DR   GeneTree; ENSGT00410000025985; -.
DR   OMA; GDTPDWP; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR   GO; GO:0090734; C:site of DNA damage; IEA:Ensembl.
DR   GO; GO:0006974; P:DNA damage response; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:Ensembl.
DR   InterPro; IPR040647; SPIN-DOC_Znf-C2H2.
DR   PANTHER; PTHR34589; SIMILAR TO RIKEN CDNA 2700081O15; 1.
DR   PANTHER; PTHR34589:SF1; SPINDLIN INTERACTOR AND REPRESSOR OF CHROMATIN-BINDING PROTEIN; 1.
DR   Pfam; PF18658; zf-C2H2_12; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022}.
FT   DOMAIN          71..134
FT                   /note="SPIN-DOC-like zinc-finger"
FT                   /evidence="ECO:0000259|Pfam:PF18658"
FT   REGION          45..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          144..326
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          342..386
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        144..159
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        214..246
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        366..386
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   386 AA;  41288 MW;  D31D19116CEFEC39 CRC64;
     MALKAEGAAL DCFEVTLKCE EGEDEEEAMV VAVIPRPEPM LRVAQQEKTP PPRPNLLEAG
     GDGCEEPKEQ VSWEQEFLVG NSPGGSGRAL CMVCGAEIQS PSADTARMHI LEQHPHTLDL
     SPSEKSNILE AWSEGVALLQ DVRAEQPSSP TSGNSGQDVE ADPDSDPDPA KMPAEIVVLL
     DSEDNPALPK RSRPRGLRPL ELPAAPVSEP GNRKPRGQRW KEPPGEEPVR KKRGRPMTKN
     LDLDPDPDPD PPSPDSPMET FAAPAEVRHF TDGSFPPGFV LQLFSHTQLR ASDSKDSPKE
     GRAAEGGLPQ PESPSPAPPP GLRGTLDLQV IRVRMEEPPA VSLLQDWSKH PQGTKSVGAG
     DTPNWPAVLS DSSTTVGGQP EAGSGV
//