ID   A0A452RLP7_URSAM        Unreviewed;      1438 AA.
AC   A0A452RLP7;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=FRAS1 related extracellular matrix 1 {ECO:0000313|Ensembl:ENSUAMP00000020047.1};
GN   Name=FREM1 {ECO:0000313|Ensembl:ENSUAMP00000020047.1};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000020047.1, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000020047.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   Ensembl; ENSUAMT00000022418.1; ENSUAMP00000020047.1; ENSUAMG00000015781.1.
DR   GeneTree; ENSGT00940000156990; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   InterPro; IPR039005; CSPG_rpt.
DR   PANTHER; PTHR45739:SF7; FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1; 1.
DR   PANTHER; PTHR45739; MATRIX PROTEIN, PUTATIVE-RELATED; 1.
DR   Pfam; PF16184; Cadherin_3; 12.
DR   PROSITE; PS51854; CSPG; 11.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..1438
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5019038728"
FT   REPEAT          40..132
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          157..244
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          265..359
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          386..497
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          519..610
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          625..720
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          762..864
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          885..992
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          1013..1112
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          1133..1225
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT   REPEAT          1246..1336
FT                   /note="CSPG"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
SQ   SEQUENCE   1438 AA;  161122 MW;  06F1D6A9AD9BBE80 CRC64;
     MYVIISFILF PLHIFFPLQK SESAWLPVYI RAGFPNQIPR AAFMAMFILE VDQFILTSLT
     TSVLDCEEDE TPKPLLVFNI TKAPLQGYVT HLWDHTRPVS SFTWKDLSDM QIAYQPPNSS
     HPVRRHYEVE VEAYDFFFER SAPITVLISI RTADTNAPRV SWNTGLSLLE GQSRAITWEQ
     FQIVDNDDIH AVQLVTVGGL QHGRLTLRGG KGFLFTVADL QAGVVRYHHD DSDSTKDFVI
     FRIFDGHHSI RHKFPINILP KDDSPPFLIS NVVIELEEEQ TILIQGSMLR ASDMDSSDDY
     IFFNITKPPQ AGEIMKKPGP GLIGYPVPGF LQRDLFNGII YYRHFGGEIF EDSFEFVLWD
     SHEPPNLSVP EVVTIHITPV DDQLPKEAPG VSRHLVVKET EVAYITKKHL HFIDTEYDRE
     LLYTITTPPF FSFGHRHLDA GKLFMADSIP KLIKNPAASG LRSFTQHAVN HMKVAYMPPM
     QDIGIHPRHV QFAFSISNQH GGTLHGICFN ITILPVDNQV PEVFTNPLKV TEGGQCVIST
     ENILVSDVDT KLDNIYLSLQ RLPQCGRVEL DGFPLNPGGT FSWGDLHALK VRYQHDGSER
     LRDDIFLEVT DGTNSAEFVL HXQCQPPILK ADLIPMMHCS EGEEVVITSE YIFATDVDSD
     DLRLTFVIVR EPQHGVVRKA GVTVDRFSQR DVIAGAVTYK HTGGEIGLVP CFDTITLVVS
     DGEAGPFVNG CCYNGPHPSV PLHESFPVYD LNITVHPVDN QSPSIARGTM FAVDEGFSAA
     ITINHLSATD PDTAADDLEF VLVSPPQFGY LENTLPSAGF EKSNMGISIA SFRWKDMKAL
     HINYVQARHL RMEPAADQFM VYATDGMRRS LEIPFYIIIN PTNDEAPDFV VQNITVCEGQ
     TKELDTSIIS AADLDVPKDP LLFSLTHKPR HGLLISGVLS KDFPRNKQPV NPGQKHDLVQ
     NFSLERLKNG MKLMYVHDDS ESLADDFTIQ LSDGKHKILK TISVEIIPVN DEKPMLSKKA
     EITMKMGETR IISSAILSAI DEDSPREKIY YLFERLPQNG QLQLKVSIGR DWVPLYPGMK
     CTQEEVDLNL LRYTHTGAMD SQDRDSFTFY LWDGDNRSPA FDCHITIKDM GKGDIVIFGK
     PLVVPKGDRG FLTTTTLLAV DGTDKPEDLL YVITSPPRYG QVEYVRYPGV PITSFSQMDI
     AGQTVCYVHK SKAAVSSDTF RFIISNGLQT KHGMFEIILE TVDRALPMVT RNRGLRLAEG
     STGLLSPDLL QLTDPDTPVE NLTFVLARLP QYGQLYLRGT VPLQHNFTQR DVDRRDVAYR
     HLGGGSQVDY FTFVATDRTN QGFVVDGRVS QEPISFTIQV DRLDKTAPYI THLHSASQVG
     LLKNGCYGIY LTSHVLKASD PDTDDNLIIF KILRGPQHGH LENTTTGTAF LNPCNCSS
//