ID   A0A452RMZ0_URSAM        Unreviewed;       185 AA.
AC   A0A452RMZ0;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Intraflagellar transport protein 22 homolog {ECO:0000256|ARBA:ARBA00040799};
DE   AltName: Full=Rab-like protein 5 {ECO:0000256|ARBA:ARBA00041562};
GN   Name=IFT22 {ECO:0000313|Ensembl:ENSUAMP00000020556.1};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000020556.1, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000020556.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Small GTPase-like component of the intraflagellar transport
CC       (IFT) complex B. {ECO:0000256|ARBA:ARBA00037285}.
CC   -!- SUBUNIT: Component of the IFT complex B, at least composed of IFT20,
CC       IFT22, IFT25, IFT27, IFT46, IFT52, TRAF3IP1/IFT54, IFT57, IFT74, IFT80,
CC       IFT81, and IFT88. Interacts with IFT88.
CC       {ECO:0000256|ARBA:ARBA00038816}.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC       {ECO:0000256|ARBA:ARBA00006270}.
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DR   AlphaFoldDB; A0A452RMZ0; -.
DR   STRING; 9643.ENSUAMP00000020556; -.
DR   Ensembl; ENSUAMT00000022966.1; ENSUAMP00000020556.1; ENSUAMG00000016178.1.
DR   GeneTree; ENSGT00390000013187; -.
DR   OMA; WYSMFIS; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   GO; GO:0030992; C:intraciliary transport particle B; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24073; DRAB5-RELATED; 1.
DR   PANTHER; PTHR24073:SF528; INTRAFLAGELLAR TRANSPORT PROTEIN 22 HOMOLOG; 1.
DR   Pfam; PF08477; Roc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022}.
SQ   SEQUENCE   185 AA;  20848 MW;  291D850929FCDF17 CRC64;
     MLKAKILFVG PCESGKTVLA NFLTESSDIT EYNPTQGVRI LEFENPHVTS NTKGTGCEFE
     LWDCGGDPKF ESCWPALMKD SHGVVIVFNA DLPSHLKEIE MWYSCFVQQQ FLQDTQCLLI
     AHHKPGSGSD KGNLTLSPPL NKLKLVHSNL EDDPEEIRLE FIKYLKSIIN SVSESRDREE
     MSIIT
//