ID A0A452RNG2_URSAM Unreviewed; 688 AA.
AC A0A452RNG2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Protein tyrosine phosphatase receptor type K {ECO:0000313|Ensembl:ENSUAMP00000020714.1};
GN Name=PTPRK {ECO:0000313|Ensembl:ENSUAMP00000020714.1};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000020714.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000020714.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A452RNG2; -.
DR Ensembl; ENSUAMT00000023154.1; ENSUAMP00000020714.1; ENSUAMG00000016227.1.
DR GeneTree; ENSGT00940000156249; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR19134; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR19134:SF209; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE KAPPA; 1.
DR Pfam; PF00102; Y_phosphatase; 2.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 2.
DR SMART; SM00404; PTPc_motif; 2.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 2.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 2.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000291022}.
FT DOMAIN 136..390
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 310..381
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT DOMAIN 422..684
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 598..675
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 688 AA; 78902 MW; A64EEBEA919B3FA5 CRC64;
GIVIVTLAKK RKDAMGNTRQ EMTHMVNAMD RSYADQSTLH AEDPLSITFM DQHNFSPRCK
FFIKILIMPN DPLVPTAVLD ENHSATAESS RLLDVPRYLC EGTESPYQTG QLHPAIRVAD
LLQHINLMKT SDSYGFKEEY ESFFEGQSAS WDVAKKDQNR AKNRYGNIIA YDHSRVILQP
VEDDPSSDYI NANYIDVSIF IVWCAQFVGP VHETVYDFWR MIWQEQSACI VMVTNLVEVG
RVKCYKYWPD DTEVYGDFKV TCVEMEPLAE YVVRTFTLER RGYNEIREVK QFHFTGWPDH
GVPYHATGLL SFIRRVKFSN PPSAGPIVVH CSAGAGRTGC YIVIDIMLDM AEREGVVDIY
NCVKALRSRR INMVQTEEQY IFIHDAILEA CLCGETAIPV CEFKAAYFDM IRIDSQTNSS
HLKDEFQTLN SVTPRLQAED CSIACLPRNH DKNRFMDMLP PDRCLPFLIT IDGESSNYIN
AALMDSYRQP AAFIVTQYPL PNTVKDFWRL VYDYGCTSIV MLNEVDLSQG CPQYWPEEGM
LRYGPIQVEC MSCSMDCDVI NRIFRICNLT RPQEGYLMVQ QFQYLGWASH REVPGSKRSF
LKLILQVEKW QEECEEGEGR TIIHCLNGGG RSGMFCAIGI VVEMVKRQNV VDVFHAVKTL
RNSKPNMVEA PEQYRFCYDV ALEYLESS
//
