ID   A0A452RNZ9_URSAM        Unreviewed;      1754 AA.
AC   A0A452RNZ9;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Periplakin {ECO:0000313|Ensembl:ENSUAMP00000020963.1};
GN   Name=PPL {ECO:0000313|Ensembl:ENSUAMP00000020963.1};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000020963.1, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000020963.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   Ensembl; ENSUAMT00000023420.1; ENSUAMP00000020963.1; ENSUAMG00000016486.1.
DR   Ensembl; ENSUAMT00000023423.1; ENSUAMP00000020966.1; ENSUAMG00000016486.1.
DR   GeneTree; ENSGT00940000153578; -.
DR   OMA; YRSVKQK; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR   Gene3D; 1.20.58.60; -; 4.
DR   Gene3D; 3.30.160.780; -; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR041615; Desmoplakin_SH3.
DR   InterPro; IPR043197; Plakin.
DR   InterPro; IPR035915; Plakin_repeat_sf.
DR   InterPro; IPR001101; Plectin_repeat.
DR   InterPro; IPR018159; Spectrin/alpha-actinin.
DR   PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR   PANTHER; PTHR23169:SF10; PERIPLAKIN; 1.
DR   Pfam; PF17902; SH3_10; 1.
DR   SMART; SM00250; PLEC; 2.
DR   SMART; SM00150; SPEC; 4.
DR   SUPFAM; SSF75399; Plakin repeat; 1.
DR   SUPFAM; SSF46966; Spectrin repeat; 3.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          388..451
FT                   /note="Desmoplakin SH3"
FT                   /evidence="ECO:0000259|Pfam:PF17902"
FT   COILED          22..49
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          254..281
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          355..382
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          588..615
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          758..816
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          890..924
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          948..1220
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1246..1280
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1306..1438
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1464..1590
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1754 AA;  204459 MW;  14A34612D516A2C6 CRC64;
     RAPLWRSRAP AHPLLSTCSI SNKELSELIE QLQKNADQVE KNIVDTEAKM QSDLARLQEG
     QQPEHRDVTL QKVSDSEKLL YVLEADAAIA KHMKHPQGDM IAEDIRQLKE RVTSLRGKHK
     QIYNLVVKEV DPQVNWAALV DEKLDKLSSQ SFGTDLPLVD HQVEQHNIFH KEVKAIGPHL
     AKDGGKEQNS ELQAKYQKLL AASQVRQQHL STLQDYMQRC TNELYWLDQQ AKGRMQYDWS
     DRNLDYPSRR RQYENFINRN LEAKEERINK LHSEGDQLLA AEHPGRNSIE AHMEAVHADW
     KEYLNLLICE ESHLKYMEDY HQFHRDVRDA QELLRKVDSD LDHKYSPDFK DQYQLELLLR
     ELDDQEKALD KYEHVVRGLQ KRGQQVVPLK YRRETPLKPI PVEALCDFEG DRGLISRGYS
     YTLQSNNGES WDLTDSAGNK LTAPAICFVI PPTDPEALAL ADSLAGQYRS VRQKAARSRG
     ALQQRHEVLK AETPGDASDL QGRHLLAGLD KVARDLDRQE KAITGILRPP LEQGRAVQDS
     AERAKDLKNI TNELLRIEPE KARSTAECKE FVQALPGSGT TPLLKTRVAD TNRKYERLVQ
     LLDLAQEKVD VANRLEKSLQ QGWEALATYE KQLTQEDTVP ESGRALDSKR QELVALASEL
     QAQKSLLGEV EQNLEAAKQC SSSLASRFQE HCPDLERQEA EVHKLRQRSD NLRQQVELRA
     QSLQIARAAY DDYRSGYDHV LQFLSQIPSY EPQETDSLSQ METKLKNQKN LLDEIARREQ
     EVHEVCTHSQ QYQQAVKDYE LEAEKLRSLL DLENGRSSHV SKRARLHSPA AKVREEEAAL
     AAKFTEVNAI NRQRLQNLEF ALSLLRQQPE VGASHEILQG STPGSTVEET WKVQKELDEE
     IERRQQLEKE VKSAQEELKT LQKRSPQESV VKKEVLKKVP DPALEESFQQ MQRTLVEEQH
     KNQLLQEELE TLRLRLHALE QETRDGGQEY VVKEVLRIEP DRAQEDEVLK LREELEELRR
     QKGTREAEVA LLQQRIAALA EEKNRAQEKV TEKEVVKLQN DPQLEAEYRQ LQEARQREGK
     LREEREEELT FLQDKLKRLE KERAMAEGKI TVKEVLKVEK DVATEREVGD LKHQYEDEEA
     KARANQREKT ELLRKIWALE EENARVLVQE KVREIVRPDP EAEREVANLR LELVEQERKY
     RAAEEQLKSY QSELEALRRR GPQVEVKEVT KEVIKYKTDP EMEKELQRLR EEIVDKTRLI
     ERCDLEIYQL KQEIQSLKDT KPQVQTKEVV QEILQFQEDP QTKEEVQSLR ARLSEEQKKQ
     VDLERERASQ EEKIRQKEEE LSQVKERVVQ QEVVRYEEEP SLRAEVNAFT ESIDMELRQI
     DNLRGELRRL QRRRAELERQ LEELERERQA RREAELEVQR LKQRLADLEK EEGEAREKVT
     LKQKVVLQQD PQQAREHSLL KVQLEEERHR RQVLESELET LKKKLVNLEK MEVKEKVVFS
     ESIQVEKGDT EQEIQKLKNS LEEESRSKRE LDAEVSRLEA KLSELEFCNS KSSKELDFLR
     EENHRLQLER QSLQLETRRL QSEIEMAATE TRDLRNMTTA DSGTNLDSRL WSLERELDDL
     KRLSKDKDLE IDELQKRLGS VAVKREQREN HLRRSIVVID PDTGRELSPE EAHRAGLIDW
     NMFVKLRSQE CDWEEISVKG PSGESSVIHD RKSGRKFSIE EALQKGRLTP AQYDRYVNKD
     MSIQELAVLV SGQK
//