ID A0A452RQ31_URSAM Unreviewed; 653 AA.
AC A0A452RQ31;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Erythrocyte membrane protein band 4.1 like 4A {ECO:0000313|Ensembl:ENSUAMP00000021387.1};
GN Name=EPB41L4A {ECO:0000313|Ensembl:ENSUAMP00000021387.1};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000021387.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000021387.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A452RQ31; -.
DR Ensembl; ENSUAMT00000023900.1; ENSUAMP00000021387.1; ENSUAMG00000016360.1.
DR GeneTree; ENSGT00940000159623; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13186; FERM_C_NBL4_NBL5; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF4; BAND 4.1-LIKE PROTEIN 4A; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000291022}.
FT DOMAIN 1..283
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 314..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..395
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..412
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..455
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..473
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..501
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..585
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..614
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 621..647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 653 AA; 75029 MW; 86520E47CE4D06CB CRC64;
PLKWIIFKIN MVCEVVLKST KGSVVLDHVF RHIDLVEIDY FGLRYCDRSH QTYWLDPAKT
LAEHKELINT GPPYTLYFGI KFYAEDPCKL KEEITRYQFF LQVKQDVLQG RLPCPLNIAA
QLGAYAVQSE LGDYDPYKHT TGYVSEYRFV PDQKEELEEA IERIHKTLMG QAPSEAELNY
LRTAKSLEMY GVDLHPVYGE NKSEYFLGLT PVGVVVYKNK KQVGKYFWPR ITKVHFKETQ
FELRVLGKDC NETSFFFEAR SKTACKHLWK CGVEHHTFFR MPENESNSLS RKLSKFGSMS
YKHRYSGRTA LQMSRDVSIQ LPRPDQNVAR SRSKTYPKRI TQTQPAGSNG INRVTANIEN
GENEGTTKII APSPIKSFKK AKNENSPDTQ RSKSHAPWEE NGPQSGLYSS PNDRMKSPKC
PYTRRRNPSC GSDDSVQPTR RRSRSRCNTS SGSESENSNR EHRKKRNRTR QENDMVDSAP
QWEAVLRRQK EKNQADPNNR RSRHRSRSRS PDIQAKEELW KHIQKELVDP SGLSEEQLKE
IPYTKVETQG DPIRIRHSHS PRSYRQYRRS QCSDGERSVL SEVNSKTDLV PPLPVTRSSD
AQGSGGSTVH QRRNGSKDSL IEEKSQTSTS NLAGKHTAKT VKTVQASRLK IET
//
