ID A0A452RQM6_URSAM Unreviewed; 392 AA.
AC A0A452RQM6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Methionyl-tRNA formyltransferase, mitochondrial {ECO:0000256|ARBA:ARBA00014185};
DE EC=2.1.2.9 {ECO:0000256|ARBA:ARBA00012261};
GN Name=MTFMT {ECO:0000313|Ensembl:ENSUAMP00000021609.1};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000021609.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000021609.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the Fmt family. {ECO:0000256|ARBA:ARBA00010699}.
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DR AlphaFoldDB; A0A452RQM6; -.
DR STRING; 9643.ENSUAMP00000021609; -.
DR Ensembl; ENSUAMT00000024149.1; ENSUAMP00000021609.1; ENSUAMG00000016965.1.
DR GeneTree; ENSGT00390000017828; -.
DR OMA; RKVWQNV; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0004479; F:methionyl-tRNA formyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd08646; FMT_core_Met-tRNA-FMT_N; 1.
DR Gene3D; 3.40.50.12230; -; 1.
DR InterPro; IPR005794; Fmt.
DR InterPro; IPR005793; Formyl_trans_C.
DR InterPro; IPR002376; Formyl_transf_N.
DR InterPro; IPR036477; Formyl_transf_N_sf.
DR InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR InterPro; IPR041711; Met-tRNA-FMT_N.
DR NCBIfam; TIGR00460; fmt; 1.
DR PANTHER; PTHR11138; METHIONYL-TRNA FORMYLTRANSFERASE; 1.
DR PANTHER; PTHR11138:SF5; METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF02911; Formyl_trans_C; 1.
DR Pfam; PF00551; Formyl_trans_N; 1.
DR SUPFAM; SSF50486; FMT C-terminal domain-like; 1.
DR SUPFAM; SSF53328; Formyltransferase; 1.
PE 3: Inferred from homology;
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 121..224
FT /note="Formyl transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00551"
FT DOMAIN 247..353
FT /note="Formyl transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02911"
SQ SEQUENCE 392 AA; 43386 MW; FB6D4AF36907CEFB CRC64;
MRVLVRRCWG SRPVGGGPSG RPIPQWRALA GLGGSPGGED GRAVRVREKP PWRVLFFGTD
HFARETLRAL HAARENKEEE LIEKLEVVTV PSPSPKGLPV KQYAVQSQLP VYEWPDVGSG
EYDVGVVASF GRLLSEALIF KFPYGVLNVH PSCLPRWRGP APVIHTVLHG DTVTGVTIMQ
IRPNRFDVGP ILKQETVPVP PKSTAKELEA VLSRLGADML ISVLKNLPES LSNGRQQPAE
GVTHAPKISA GTSCIKWEEQ TSEQIIRLHR AIGTIIPLQT LWMDNTIKLL DLVEVNSSVL
TDPKLRGQPV FPGSVIYHKK SQILLVCCKD GWIGVRSVML KKTLTAPDFY NGYLHPWYQN
DSQAQPSQCR FQTLRLPTKK KQGKKCNSAL SS
//
