ID A0A452RSR5_URSAM Unreviewed; 562 AA.
AC A0A452RSR5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Metastasis associated 1 family member 3 {ECO:0000313|Ensembl:ENSUAMP00000022384.1};
GN Name=MTA3 {ECO:0000313|Ensembl:ENSUAMP00000022384.1};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000022384.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000022384.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452RSR5; -.
DR Ensembl; ENSUAMT00000025019.1; ENSUAMP00000022384.1; ENSUAMG00000017598.1.
DR GeneTree; ENSGT01030000234573; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd11661; SANT_MTA3_like; 1.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 4.10.1240.50; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR040138; MIER/MTA.
DR InterPro; IPR035170; MTA1_R1.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR000679; Znf_GATA.
DR PANTHER; PTHR10865; METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN; 1.
DR PANTHER; PTHR10865:SF6; METASTASIS-ASSOCIATED PROTEIN MTA3; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF01448; ELM2; 1.
DR Pfam; PF00320; GATA; 1.
DR Pfam; PF17226; MTA_R1; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM01189; ELM2; 1.
DR SMART; SM00717; SANT; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51038; BAH; 1.
DR PROSITE; PS51156; ELM2; 1.
DR PROSITE; PS51293; SANT; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1..84
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 85..196
FT /note="ELM2"
FT /evidence="ECO:0000259|PROSITE:PS51156"
FT DOMAIN 203..255
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 356..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 514..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..538
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 562 AA; 63810 MW; D85F1A77E010B33C CRC64;
MHKREESETT IEADLTDKQK HQLKHRELFL SRQYESLPAT HIRGKCSVAL LNETESVLSY
LDKEDTFFYS LVYDPSVKTL LADKGEIRVG PRYQADIPEM LLEGESDERE QSKLEVKVWD
PNSPLTDRQI DQFLVVARAV GTFARALDCS SSVRQPSLHM SAAAASRDIT LFHAMDTLYR
HSYDLSSAIS VLVPLGGPVL CRDEMEEWSA SEASLFEEAL EKYGKDFNDI RQDFLPWKSL
TSIIEYYYMW KTTDRYVQQK RLKAAEAESK LKQVYIPTYK PNPNQISASN GKPGAVNGAV
GTTFQPQNPL LGRACESCYA TQSHQWYSWG PPNMQCRLCA TCWLYWKKYG GLKMPSQSEE
EKLSPSPTTE DPRVRSHMSR QAMQGMPVRN TGSPKSAVKT RQAFFLHTTY FTKFARQVCK
NTLRLRQAAR RPFVPINYAA IRAEYADRHA ELSGSPLKSK STRKPLACII GYLEIHPSKK
PNVIRSTPSL QTPTTKRMLT TPNHTSLSIL GKRNYSHHNG LDGEQEHGGH RKPPPSPRLG
EQNEEVRFFL LLEAQGGPRS KN
//
