ID A0A452SDK8_URSAM Unreviewed; 1027 AA.
AC A0A452SDK8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Ankyrin repeat and FYVE domain containing 1 {ECO:0000313|Ensembl:ENSUAMP00000030438.1};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000030438.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000030438.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452SDK8; -.
DR Ensembl; ENSUAMT00000033961.1; ENSUAMP00000030438.1; ENSUAMG00000022937.1.
DR GeneTree; ENSGT00940000156179; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd18501; BACK_ANKFY1_Rank5; 1.
DR CDD; cd15728; FYVE_ANFY1; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 6.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR049764; ANFY1_FYVE.
DR InterPro; IPR049763; ANKFY1_BACK.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24118; POTE ANKYRIN DOMAIN; 1.
DR PANTHER; PTHR24118:SF82; RABANKYRIN-5; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 4.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF01363; FYVE; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 21.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 6.
DR PROSITE; PS50088; ANK_REPEAT; 11.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT REPEAT 183..226
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 348..380
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 400..432
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 479..511
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 512..544
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 627..659
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 728..760
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 763..795
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 796..828
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 829..850
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 901..933
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 962..1022
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
SQ SEQUENCE 1027 AA; 112345 MW; 82ECA56462F86408 CRC64;
RQYTSYSCAL FIYECEKSVM SLVNVRNCIR FYQTAEELSA STLMNYCAEI IASHWDDLRK
EDFSSMSAQL LYKMMKSKTE YPLHKAVRVE REDVVFLYLI EMDSQLPGKL NEVDHHGDLA
LDLALSRRLE SIATTLVSHK ADVDMVDKNG WSLLHKGIQR GDLFAATFLI KNGALVNAAT
LGAQETPLHL VALYSAKKHS ADVMSEMAQI AEALLQAGAN PNMQDSRGRW HCSVRRGLYV
LLALLPHFRL DLELKDHEGS TALWLAVQYV TVSPDHSVNP FEDLPVVNGT SFDENSFAAR
LIQRGSNTNA PDAVTGNCLL QRAAEAGNEA AALFLATSGA QVNHRNKWGE TPLHTACRHG
LANLTAELLQ QGANPNLQTE EAPPLPKEAA SLTSSVDSVY LQTPLHMAIA CNHPDVVSVI
LEQKANALHA TNNLQIIPDF SLKDSRDQTV LGLALWTGMH TIAAQLLGSG ACINDTMSDG
QTLLHMAMQR QDSKSALFLL EHQADINVRT QDGETALQLA IRNQLPLVVD AICTRGADMS
VPDEKGNSPL WLALAGNLED IASTLVRHGC DATCWGPGPG GCLQTLLHRA IDENNESTAC
FLIRSGCDVN SPRQPGPNGE GEEEARDGQT PLHLAASWGL EETVQCLLEF GASVNTQDAE
GRAPVHVAIS NQHSVIIQLL ISHPDIHLSV RDRQGLTPFA CAMTYKNNRA AEAILKRESG
AAEQVDNKGR NFLHVAVQNS DIESVLFLIS VQANVNSRVQ DASKLTPLHL AVQAGSEIIV
RNLLLAGAKV NELTKHRQTA LHLAAQQDLP TICSVLLENA VDFAALDENG NNALHLAVMH
GRLNNIRVLL TECTVDAEAF NLRGQSPLHI LGQYGRENAA TIFELFLECM PEYPLDKPDA
EGNTVLLLAY MKGNANLCRA VVRAGARLGV NNNQGVNIFN YQVATKQLLF RLLDMLSKEP
PWCDGSTCYE CAAKFGVTTR KHHCRHCGRL LCHKCSTKEI PIIKFDLNKP VRVCNICFDV
LTLGGVS
//
