ID A0A452SEN9_URSAM Unreviewed; 343 AA.
AC A0A452SEN9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=SRCR domain-containing protein {ECO:0000259|PROSITE:PS50287};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000030899.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000030899.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR AlphaFoldDB; A0A452SEN9; -.
DR Ensembl; ENSUAMT00000034471.1; ENSUAMP00000030899.1; ENSUAMG00000023723.1.
DR GeneTree; ENSGT00940000162108; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR Gene3D; 3.10.250.10; SRCR-like domain; 3.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48071:SF15; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 3.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 3.
DR SUPFAM; SSF56487; SRCR-like; 3.
DR PROSITE; PS50287; SRCR_2; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..343
FT /note="SRCR domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019212308"
FT DOMAIN 22..122
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 135..235
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 235..335
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 47..111
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 91..101
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 160..224
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 204..214
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 260..324
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 273..334
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 304..314
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 343 AA; 36671 MW; 77F4C8A4DE7A8551 CRC64;
MQNVFLLLTC TIFVSLKDWP QLQLVNGSGR CSGRVEVFYH GQWGRVCDDH WDMNEADVVC
RQLHCGRATA APTGAHFGAG SGKILLDDVQ CAGTESHLGE CEHRAEAGHN CGHLEDANAE
LPNSSLLFKL SWMAVRLVNG TGRCSGRVEI HIQGMWGTVC DDLWDLAEAT VVCRQLQCGQ
AMAAPTGAHF GAGSGKILLD DVQCAGTESH LGECEHRAEA GHNCGHLEDA AWMAVRLVNG
TGRCSGRVEV HIQGMWGTVC DDLWDLAEAT VVCRQLQCGQ ATAAPTGAHF GAGSGKILLD
DVQCAGTESH LGECEHRAEA GHNCGHLEDA SVICAGLWDY DLS
//
