ID   A0A452SIC7_URSAM        Unreviewed;       219 AA.
AC   A0A452SIC7;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Beta-sarcoglycan {ECO:0000256|ARBA:ARBA00015329};
GN   Name=SGCB {ECO:0000313|Ensembl:ENSUAMP00000032295.1};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000032295.1, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000032295.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Component of the sarcoglycan complex, a subcomplex of the
CC       dystrophin-glycoprotein complex which forms a link between the F-actin
CC       cytoskeleton and the extracellular matrix.
CC       {ECO:0000256|ARBA:ARBA00002860}.
CC   -!- SUBUNIT: Cross-link to form 2 major subcomplexes: one consisting of
CC       SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The
CC       association between SGCB and SGCG is particularly strong while SGCA is
CC       loosely associated with the other sarcoglycans.
CC       {ECO:0000256|ARBA:ARBA00026041}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC       {ECO:0000256|ARBA:ARBA00004274}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004274}.
CC   -!- SIMILARITY: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
CC       {ECO:0000256|ARBA:ARBA00007574}.
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DR   AlphaFoldDB; A0A452SIC7; -.
DR   STRING; 9643.ENSUAMP00000032295; -.
DR   Ensembl; ENSUAMT00000035997.1; ENSUAMP00000032295.1; ENSUAMG00000024691.1.
DR   GeneTree; ENSGT00390000008110; -.
DR   OMA; ESGAMRI; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   GO; GO:0016012; C:sarcoglycan complex; IEA:InterPro.
DR   GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR   GO; GO:0007517; P:muscle organ development; IEA:InterPro.
DR   InterPro; IPR006875; Sarcoglycan.
DR   InterPro; IPR027659; Sgcb.
DR   PANTHER; PTHR21142:SF2; BETA-SARCOGLYCAN; 1.
DR   PANTHER; PTHR21142; SARCOGLYCANS; 1.
DR   Pfam; PF04790; Sarcoglycan_1; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022}.
SQ   SEQUENCE   219 AA;  24131 MW;  D5456C04EA7DD79F CRC64;
     MEFHESGLLR FKQVSDMGVI HPLYKSTVGG RRNENLVITG NNQPIVFQQG TTKLSVEKNK
     TSITSDIGMQ FFDPRTQNIL FSTDYETHEF HLPSGVKSLN VQKASTERIT SNATSDLNIK
     VDGRAIVRGN EGVFIMGKTI EFHMGGNMEL KAENSIILNG TVMVSTTRLP SSSSGDQFGT
     GDWVRYKLCM CADGTLFKVQ VTGRNMGCQI SDNPCGNTH
//