ID   A0A452SN22_URSAM        Unreviewed;      1044 AA.
AC   A0A452SN22;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Transport and golgi organization 6 homolog {ECO:0000313|Ensembl:ENSUAMP00000033994.1};
GN   Name=TANGO6 {ECO:0000313|Ensembl:ENSUAMP00000033994.1};
OS   Ursus americanus (American black bear) (Euarctos americanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000033994.1, ECO:0000313|Proteomes:UP000291022};
RN   [1] {ECO:0000313|Proteomes:UP000291022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA   Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT   "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT   in black bear kidneys.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSUAMP00000033994.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the Tango6 family.
CC       {ECO:0000256|ARBA:ARBA00005724}.
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DR   AlphaFoldDB; A0A452SN22; -.
DR   STRING; 9643.ENSUAMP00000033994; -.
DR   Ensembl; ENSUAMT00000037864.1; ENSUAMP00000033994.1; ENSUAMG00000025900.1.
DR   GeneTree; ENSGT00390000010938; -.
DR   OMA; QVATLIC; -.
DR   Proteomes; UP000291022; Unassembled WGS sequence.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR019451; Rtp1_C1.
DR   InterPro; IPR019414; Rtp1_C2.
DR   InterPro; IPR039600; TANGO6/Rtp1.
DR   PANTHER; PTHR20959; TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER; 1.
DR   PANTHER; PTHR20959:SF1; TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG; 1.
DR   Pfam; PF10363; RTP1_C1; 1.
DR   Pfam; PF10304; RTP1_C2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000291022}.
FT   DOMAIN          789..900
FT                   /note="RNA polymerase II assembly factor Rtp1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10363"
FT   DOMAIN          992..1024
FT                   /note="RNA polymerase II assembly factor Rtp1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10304"
FT   REGION          718..783
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        723..749
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1044 AA;  115918 MW;  21B0F035D04F5D9B CRC64;
     VTLNSNLSTL EDKLLKDPHW RKLKFLRDEI ANKAEWPQNS VDVTWSFSSQ ALLLLLCLKE
     TMIHLAADFS PGKPNLRTPE AAPALSPDTL SISQQKTVQS ALQFVVTLGV CPYLMPGVGV
     PLRCRTEFGA VVQDVVCLDV PPHATRRLYS SCKVLLNVAH HTSLGSLIFC RHFGDLAAGL
     CQLGFCPTKR KPLNPEEEVL TEEERTLSRE ALRDILDQVY QPLAVRELLI LQGGPPQPCT
     DEKTQVRYRA PAWLRRLCGQ LLSERLMRPS GVQAVVRGIL EGAGAGAAGG SDGEAAAADW
     KKCDLIAKIL ASCPQQCLSP EDYYRDICPQ ILDLFHFQDK LTARQFQRVA TTTFITMSRE
     RPQLASKYLL QPVLAPLHRC LNTAEIPESD MVPGIILVTE EELTRCIEDV FKVYVVGNEP
     VTVLVDSLLP VLGVLFSLYC FTKQSVSHIR SLCQEILLWI LGKLERRKAI ASLKGFAGLD
     KSVSSLHSLC QFRAAAQGGI MVTIKEAICD EDEDEALYQK VSSEQCQVEH LGDLLAHCQE
     CGLAGDFFIF CLKELTHVAV ENEAELKTKP FSSKSLLELE QHQTLVEGQE QKLLVLQLLA
     ALCERMSEQI FTNITQVVDF VAATLQRACA SLAHQAESTV ESQTLSMSMG LVAVMLGGAV
     QLKSSDFAIL KQLLPLLEKV SKVYPDPVIQ ELAVDLRITI STHGAFSTEA VSVAAQSTLN
     KKDPQGKMEE QQQTSHESYS DDSHLKQQQS PEKSKQTGLK SNAPLIPQEV RGPRTITNQK
     SGSVTTDQLQ EVLLSAYDPQ IPTRAAALRT LSRWIEQRET KALEMQEKLL KIFLENLEHE
     DAFVYLSAIQ GVALLSDAYP EKILLGLLAQ YDSDKNKHTP ETRMKVGEVL MRIVKALGDM
     VSKYREPLIH TFLRGARDPD SVHRASSLSN LGELCQRLDF LLGSVVHEVT ACLIAVAKTD
     HEVQVRRAAV HVIVLLLRGL SQKATEVLKD VLKDLYHLLK HVVCLESDNV AKLHAQLALE
     ELDEIMRNFL FPPQKLEKKI VVLP
//