ID A0A452SPP6_URSAM Unreviewed; 583 AA.
AC A0A452SPP6;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=PDZ and LIM domain 5 {ECO:0000313|Ensembl:ENSUAMP00000034680.1};
GN Name=PDLIM5 {ECO:0000313|Ensembl:ENSUAMP00000034680.1};
OS Ursus americanus (American black bear) (Euarctos americanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=9643 {ECO:0000313|Ensembl:ENSUAMP00000034680.1, ECO:0000313|Proteomes:UP000291022};
RN [1] {ECO:0000313|Proteomes:UP000291022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Korstanje R., Srivastava A., Sarsani V.K., Sheehan S.M., Seger R.L.,
RA Barter M.E., Lindqvist C., Brody L.C., Mullikin J.C.;
RT "De novo assembly and RNA-Seq shows season-dependent expression and editing
RT in black bear kidneys.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSUAMP00000034680.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A452SPP6; -.
DR STRING; 9643.ENSUAMP00000034680; -.
DR Ensembl; ENSUAMT00000038615.1; ENSUAMP00000034680.1; ENSUAMG00000026300.1.
DR GeneTree; ENSGT00940000155292; -.
DR Proteomes; UP000291022; Unassembled WGS sequence.
DR GO; GO:0015629; C:actin cytoskeleton; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd09453; LIM1_ENH; 1.
DR CDD; cd09459; LIM3_ENH; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 3.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24214:SF32; PDZ AND LIM DOMAIN PROTEIN 5; 1.
DR PANTHER; PTHR24214; PDZ AND LIM DOMAIN PROTEIN ZASP; 1.
DR Pfam; PF00412; LIM; 3.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00132; LIM; 3.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 3.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 3.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000291022};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 1..65
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 405..463
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 464..523
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 524..583
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 86..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 293..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 583 AA; 63185 MW; AC60986C5B2F99B6 CRC64;
QIDTPNEIYL FQLKDGGKAS QANVRIGDVV LSIDGISAHG MTHLEAQNKI KGCTGSLNMT
LQSAGKPAVN VPRQPTVTSV CSETAQELAE GQRRGSQGDI KQQNGPPRKH IVERNTEFYH
IPTHSDASKK RLIEDTEDWR PRTGTTQSRS FRILAQITGT EHCKFDSSLE DLPQSGPHPP
ATPQVLHIGG QVATLSKVTT FSSSSTRNVV TSSLEGFRNF STFSSPVKYS AAVLSSAAAT
VSAVLAAKTR LSSPDKYHSL LDALCISPVS RPLAFSYLQS SRKSTGSIHV KKISNTQETS
QQLAPSVASA RSMPERRESP ASTRPGVTGF TTAAAFRPPG SANIVKSPSW PQPNQAALST
GRISNSAASP GAVAPANSAG GQPQPGDQDT LVQRAEHIPA GKRTPMCAHC NQVIRGPFLV
ALGKSWHPEE FNCAHCKNTM AYIGFVEEKG ALYCELCYEK FFAPECGRCQ RKILGEVINA
LKQTWHVSCF VCVACGKPIR NNVFHLEDGE PYCETDYYAL FGTICHGCEF PIEAGDMFLE
ALGYTWHDTC FVCSVCCESL EGQTFFSKKD KPLCKKHAHS VNF
//
