ID A0A452YMY8_AEGTS Unreviewed; 876 AA.
AC A0A452YMY8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET1Gv20474500.11, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET1Gv20474500.11}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
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DR AlphaFoldDB; A0A452YMY8; -.
DR EnsemblPlants; AET1Gv20474500.11; AET1Gv20474500.11; AET1Gv20474500.
DR Gramene; AET1Gv20474500.11; AET1Gv20474500.11; AET1Gv20474500.
DR Proteomes; UP000015105; Chromosome 1D.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR CDD; cd18809; SF1_C_RecD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049163; Pif1-like_2B_dom.
DR PANTHER; PTHR10492:SF94; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR Pfam; PF05970; PIF1; 1.
DR Pfam; PF21530; Pif1_2B_dom; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT DOMAIN 738..784
FT /note="DNA helicase Pif1-like 2B"
FT /evidence="ECO:0000259|Pfam:PF21530"
SQ SEQUENCE 876 AA; 98851 MW; C14D08C40DE5A7E9 CRC64;
MNSNYKLVVP EQYDRVISAE LPDRHKYPEL YAMVVKHMMH GSCGNLNPKN VCMQDLKCKS
KYPRPFNQNT LQGKDSYPVY RRRDDGRQAK IRRQMLDNRW VVPYNPYLLR MFNCHINVEV
CSSIKAVKYL YKYVYKGHDR ASFSIDQPDS NGVVDEIKRY VDARWVTPPE AMWRIFGFNL
SESFPSVLQL PLHLPNMNSV TFKAGEDLTD VVARDTASKS MLTEYFLANQ QHVWARDILY
KDFPGSFTWQ RQKYWKRREK QHQVGRIVSA HPAEGERYFL RVLLNHVPGK TSFEDLRTVD
GVLCASFREA AERLGLIEAD NTLDECLTES TQFAMPASLR RLFATILVFC EPGDVRGLWD
RHLDAMSDGY HRTHACSKAV EQMVLLDIRG MLQSMGKDIA LFPLPGIDET YDTTGGEARE
VTEESAIKVD ANDADLASSL NPEQRLAYDE ILAAVDAGDG GVFFVDGPGG TGKTFLYRSL
LAKVQGEGKI ALATATSGVA ASIMPGGRTA HSRFKIPLNI EDRGSCSFTK QSGTAKLLHM
SSLILWDEAT MTKRQAVEAL DNSMRDIIGR RDRPFGGKTV VFGGDFRQVL PVVRKGSRGQ
IINATLRSSY LWNGMRQLRL VTNMRAHNDP WYADYLLRVG NGTEETDEEG NIRLPEDICV
PPTGDGADLE KLIDHVFPAL DDNMADPNYM TSRAILSTKN DNIDKINTRM IECFQGEEKI
YHSFDSAEDD PHGYYAPEFL NNLTPNGLPP HALKLKINCP VILLRNIDPA NGLCNGTRLV
VRGFQRNAID AEIVLGQHAG RRVFLPRIPL CPSDADIFPF KFKRKQFPIR LSFAMTINKA
RGQTIPIVGV YLPDPVFSHG QLYVALSRAT AKRNIK
//
