ID A0A453A363_AEGTS Unreviewed; 1209 AA.
AC A0A453A363;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=USP domain-containing protein {ECO:0000259|PROSITE:PS50235};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET1Gv21021600.3, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET1Gv21021600.3}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase C19 family.
CC {ECO:0000256|ARBA:ARBA00009085}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A453A363; -.
DR STRING; 200361.A0A453A363; -.
DR EnsemblPlants; AET1Gv21021600.2; AET1Gv21021600.2; AET1Gv21021600.
DR EnsemblPlants; AET1Gv21021600.3; AET1Gv21021600.3; AET1Gv21021600.
DR Gramene; AET1Gv21021600.2; AET1Gv21021600.2; AET1Gv21021600.
DR Gramene; AET1Gv21021600.3; AET1Gv21021600.3; AET1Gv21021600.
DR OMA; CSHINAC; -.
DR OrthoDB; 341654at2759; -.
DR Proteomes; UP000015105; Chromosome 1D.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR025315; DUF4220.
DR InterPro; IPR007658; DUF594.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR31325:SF230; DUF4220 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR31325; OS01G0798800 PROTEIN-RELATED; 1.
DR Pfam; PF13968; DUF4220; 1.
DR Pfam; PF04578; DUF594; 1.
DR Pfam; PF00443; UCH; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 818..1192
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 994..1057
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 697..731
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1008..1023
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1024..1045
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1209 AA; 138994 MW; DF19E061ECBA270C CRC64;
MGIQDIRDGV ASFFVMLNKE TYILFRIEIL VVLVTLLFFV MFIMDVFRRN IHNTKMATIF
SILDAVSDSI VVYLLGAMQT AKFKNRLLNQ LFPVWGLVLV SFRYNIDFIS GYGVHDQHGR
RFIEWRNVVK LLGSAFLNLS SDSRFAVPLW SLLALQILKS GYRFYVHSLT VKSVWHGKSS
EVVTEHMRAG SHSSNWKPEE CNPENMAGYK YLVYGETKQS IKFKKPQYAM YIDTARNVKK
ARRGRRPRPG RSTLITLDKI WGCYRHLLDQ DSNEGNDQKD LSLAFALSRL LRCRLEDVTL
QQKLFHINRK LVKNKILEEQ NASRAFRIME LQLSFVNDYF NTRYPMVFWC GFLSLFSNLL
LSTVTFGVVC WLAVDIHKVY KPPKNDRARV VHGVNVDMII TWVFMIFMLF KEIWEMVSYL
VSNWTRLLLV CMYAQRKEER TRNRCMEGTI SSFFKSRITS KLWHGHIDQY VFLESYDNKP
RIWNFLHYIT IGMSPKKDDG ATLHSAIDVP ECVTLAALEK LRMSLEKLSS PGIVRDQPDN
PNRNQEETII RGRSLSKAII SLSGADCDRR KGYRWACYDL PTCSHVILVW HIATSLCEME
LAQRHDVDLS KHGFLNFILS YFTSCCSSKP YLLDVDNKTE EKKKVTGRLP DELHDMYITA
NSLSRYCAYL LVSKPDVIPD SFNVPKMVLQ ETVTRSRDDI LKNCDSLKSR YDKLMEEAEK
ATKDVDDVMR KEDVVRLGAM LGKQLIGESQ KDCWEILSGV WADLLVHIAP TWNAEVHKKC
LESGGEFITY FWALLWHCGI EKSNLWLVEG LYDIVVVRGM WNGGNTCYFN AVLQSLLALD
KLRARMLGHD ALTGDLGEEL QKLFRMTTNT SGAEGVLMPD KFFSYMCKMK SDFKLGVMED
SNNMLGSLLD GLNNEEHTMV ESLFYSEVAK HVSSKECEHT SVTSGGEYLD LSLAIPPKRP
ASIEDCLDFY ATGEIKDWHC MHCSAAAASR NASLNQEDTS DYDGQPEQSE NKTYEKGESS
HQTDKQTRTP NQNNGKLPML DSNSNQMEES HREQKEEEKI YRAATVQYRI TKAAPILTIQ
LKRFDYSHTD KADKLEEHVS FQDTLDMTKF MDPGQAEDVE YKYRLVAVIV HSGPKLHEGH
NFAYVRASQI GGQQQESSGT PSWFCANDES ITQVSLQQVL ECQAYMLFYE RVELPKAEPV
VEEHLPTEH
//
