ID   A0A453ADU6_AEGTS        Unreviewed;       820 AA.
AC   A0A453ADU6;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=DUF4220 domain-containing protein {ECO:0000259|Pfam:PF13968};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET2Gv20086400.3, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET2Gv20086400.3}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   AlphaFoldDB; A0A453ADU6; -.
DR   STRING; 200361.A0A453ADU6; -.
DR   EnsemblPlants; AET2Gv20086400.3; AET2Gv20086400.3; AET2Gv20086400.
DR   Gramene; AET2Gv20086400.3; AET2Gv20086400.3; AET2Gv20086400.
DR   Proteomes; UP000015105; Chromosome 2D.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025315; DUF4220.
DR   InterPro; IPR007658; DUF594.
DR   PANTHER; PTHR31325:SF269; GENOME ASSEMBLY, CHROMOSOME: II; 1.
DR   PANTHER; PTHR31325; OS01G0798800 PROTEIN-RELATED; 1.
DR   Pfam; PF13968; DUF4220; 1.
DR   Pfam; PF04578; DUF594; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        55..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        316..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          59..402
FT                   /note="DUF4220"
FT                   /evidence="ECO:0000259|Pfam:PF13968"
FT   REGION          686..820
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        703..732
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        736..792
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   820 AA;  91296 MW;  3BAFF0D8969DB68F CRC64;
     MRTVEQLMEQ GWVYRTAQLF TIWDIQAAVL SSFAAHLVLV ILAGARRRKA SGVRMLLLWL
     AYQLGNFVAP YALTNLSLCD PSPRQQLIAF WAPFLLHHLA GPDNISALSL EDNALSGREV
     LTVASRIGGA TYVLYKHVYI GGGGGGALIP ASIIIFAVGA TKYAERAFAL WRGDLANIRS
     SSKKKGQLSR FITTCSGTLA IRSTGWERCL DDEDALMVAH AMLPLCRRAM ADSSVPADGD
     TLHASREIFG TSWDDTCKVV EMELSLMYDI LYTKEAVVHT WHGYGIRVIS PAAIAATTVL
     FGFYYSKEGQ SKPDVMITYV LLAATFLLDT SWLLRALGST WMHGFLQCSW LHHAILCTGR
     WRRLGRVIVS LDLGRLRLTA TPRSPSSYRR WSGKVGQYSL LREVTREMSL CGKAAKKIGL
     ENVWKEYQHS NTHKLSHEVK EAIFTRVTKV LRLTYQEANK HKNVGYSMTN ITTNWGQVTA
     KRFASKSEEK TVHLAFGREF QEDILVWHIA TQVFLMCGSL LHGKHSGAHA NAIKALSDYL
     MFLVAVRRHM LPGLKLRSLY ERTFESLQRV WSKDRGKAGS CCSTTEEEQL ARILRHKKDD
     ADRGWGMKDA EISIISDGAN LAIELLEAGA EEFQMPLLLE LVFNVWVDKL LHAATLCSPE
     SHAMQLSRGG ELTTIVWIMV QHAGPFTIGE KGPDDDDEEP TDDETQQVKH GDKVGEEKKA
     TDGKRGRDKE PLSDPYPGYP AEPPKPKWAS EPPPPKPKSA SDPPPPKPSL AELKPESAPP
     PGAAPPPPKT DVGEPIAVQT RAPKRRRERR RRYATLYPID
//