ID   A0A453AKZ3_AEGTS        Unreviewed;       943 AA.
AC   A0A453AKZ3;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=ATP-grasp domain-containing protein {ECO:0000259|PROSITE:PS50975};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET2Gv20178300.16, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET2Gv20178300.16}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the D-alanine--D-alanine ligase family.
CC       {ECO:0000256|ARBA:ARBA00010871}.
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DR   AlphaFoldDB; A0A453AKZ3; -.
DR   STRING; 200361.A0A453AKZ3; -.
DR   EnsemblPlants; AET2Gv20178300.16; AET2Gv20178300.16; AET2Gv20178300.
DR   Gramene; AET2Gv20178300.16; AET2Gv20178300.16; AET2Gv20178300.
DR   Proteomes; UP000015105; Chromosome 2D.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.20; -; 2.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 2.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR000291; D-Ala_lig_Van_CS.
DR   InterPro; IPR011095; Dala_Dala_lig_C.
DR   InterPro; IPR011127; Dala_Dala_lig_N.
DR   InterPro; IPR016185; PreATP-grasp_dom_sf.
DR   PANTHER; PTHR23132; D-ALANINE--D-ALANINE LIGASE; 1.
DR   PANTHER; PTHR23132:SF0; D-ALANINE-D-ALANINE LIGASE FAMILY; 1.
DR   Pfam; PF07478; Dala_Dala_lig_C; 2.
DR   Pfam; PF01820; Dala_Dala_lig_N; 2.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 2.
DR   SUPFAM; SSF52440; PreATP-grasp domain; 2.
DR   PROSITE; PS50975; ATP_GRASP; 2.
DR   PROSITE; PS00843; DALA_DALA_LIGASE_1; 1.
DR   PROSITE; PS00844; DALA_DALA_LIGASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00409}; Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW   Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00409}; Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT   DOMAIN          209..447
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
FT   DOMAIN          674..939
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
FT   REGION          15..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   943 AA;  103127 MW;  D6D68988A7ECA184 CRC64;
     RMLLSFAQPR LLPRLPSPAT ATATTARPRA PRRALSSAAK TAAAGRLRAV VSERAVEGMA
     PAAAGQEGRP LRVGLVCGGP SAERGISLNS ARSVLDHIQG EDLLVSCYYI DCGMNAFAIS
     PAQLYSNTPS DFDFKLESLA QEFSTLSEFA EHLAANVDIV FPVIHGKFGE DGGIQELLEK
     ANVPFVGTPS NECLRAFDKH NASLELDAQG FLTVPNFLVE KDKLATSELE EWFRSINLNK
     ENGKVIVKPT RAGSSIGVVV AYGANEAAEK AEGIFSEGID NKVIIEVFLE GGCEFTAIVL
     DVGTANNSEP IVLLPTEVEL QSSISSDIQE DTIFNYRRKY LPTQQVAYHT PPRFPAEVID
     CIRKGVSLLF RHFGLRDFAR IDGWFLPSPA TSLPSSENGV KFGNTEYGAV LFTDINLISG
     MEQTSFLFQQ ASKVGFSHSR ILRTIVQHAC SRFPSLVTSN NAWTALSRKM QSAKQALIIP
     NGTCKQKAFV IFGGDTSERQ VSLMSGTNVW LNLQGFDDLD VTPCLLAPSN GYSSHNEDFS
     ESSRDVWTLP YSLVLRHTTE EVHAACFEAI EPERVEITSR LRNQVMKELE RALSKQDWFA
     GFDITDEQPI KYSLQQWIDY VKEAKAVVFI AVHGGIGEDG TIQSLLESAG VPYTGPGPIA
     SRTCMDKVAT SLAVDHLASY GIHTIPKDVR AREELLKSSL VDIWNDLKAK LQTETVCVKP
     ARDGCSTGVA RLRCPEDLEV YANALRGTLP RLPANCLSKA HGVIEMPVPP PESLIFEPFI
     ETDEIIISNK SWNDSTRHLV WKGENEWLEV TVGVVGKRGE MHSLNPSITV KESGDILSLE
     EKFQGGTGIN LTPPPATIMS EDALQKCKSC IEMTANTLGL EGFSRIDAFV NVHSGEVLLI
     EVNTVPGMTP STVLIHQALT EEPPIYPHKF FRTLLDLAFA RAG
//