ID A0A453B9T0_AEGTS Unreviewed; 1263 AA.
AC A0A453B9T0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=SEC7 domain-containing protein {ECO:0000259|PROSITE:PS50190};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET2Gv20427700.24, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET2Gv20427700.24}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR AlphaFoldDB; A0A453B9T0; -.
DR EnsemblPlants; AET2Gv20427700.24; AET2Gv20427700.24; AET2Gv20427700.
DR Gramene; AET2Gv20427700.24; AET2Gv20427700.24; AET2Gv20427700.
DR Proteomes; UP000015105; Chromosome 2D.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015403; Mon2/Sec7/BIG1-like_HDS.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR032817; Mon2_C.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF312; BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 5; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF16206; Mon2_C; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF09324; Sec7-like_HDS; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT DOMAIN 246..433
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 213..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1099..1144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1164..1196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..244
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1182..1196
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1263 AA; 141530 MW; 5C63C94FB915D155 CRC64;
MNIIQRDALL LFRTLCKMSM KEESDEVATK TRLLSLELLQ GLLEGVSDLF AKNFHFIDSV
KAYLSYALLR ASVSSSPVVF QYATRIFSVL LLRFRESLKG EIGVFFPLIV LRSLDSSDSS
LSQKSSVLRM LEKVCKDSQM LADMFVNYDC DIDGPNLFER MVSALSRIAH GSQSADRAAV
ASSQTVSVKG SSIQCLVSIL KSLVDWEQAR RDSSNHGSVA ESHDDGASAR SLATDETKVQ
EDGRNQFERA KAHKSTMEAA ISEFNRKPAK GVEYLLSNKL IENKASSVAQ FLKSNASLDK
VMIGEYLGQH EEFPLDVMHA YVDSMKFSGL KFDAAIREFL KGFRLPGEAQ KIDRIMEKFA
ERYCADNPGL FKNADTAYIL AYAVIMLNTD AHNPMVWPKM SKSDFVRLNT ASDEEECAPK
ELLEELYDSI INEEIKMKDD LHAAKTSKVR PEIEEKGRLV NILNLALPRL KSASDTKAES
EKIIKQTQAV FKNQGQKRGV FHVAQQVELV RPMLEAVGWP LLATFSVTME EGDNKPRVVL
CMEGFKAGIH LTRVLGMETM RYAFLTSLVR FTFLHAPREM RSKNVEALRT LLALADMDMD
ALQDAWTAVL ECVSRLEYIT SVPSMAATVM QGSNQISRDS VVQSLKELSG KPAEQVFVNS
VKLPSDSIVE FFDGLCTISA EELKQTPPRV FSLQKLVEIS YYNMARIRLV WARIWSVLAQ
HFIAAGSHHD EKVAMYAIDS LRQLGMKYLE RAELNKFTFQ NDILKPFVIL MRNSRSEKIR
GLIVDCIVQL IKSKVGSIKS GWRCVFMIFT AAADDENEYI VESAFENVEQ VILEHFDQVV
GDCFMDCVNC LIGFANNKCT SRISLKAIAL LRICEDRLAE GFIPGGSVKP VDVLPEANFD
VTEHYWFPML AGLSDLTLDS RPEVRHCALE VLFDLLNERG HKFSSPFWES IFHRVLFPIF
DHVRHAGRDG LSSGDDWLRD TSIHSLQLIC NLFNTFYKEV SFMLPPLLGL LLECAKKTDQ
TVVSIALGAL VHLIEVGGHQ FSDGDWETLL KSIRDASYTT QPLELLNSLG FQKTSNQQLL
SRESETDASS YHDIREGEAS ISNNGEQEGH QETSPRIGLE NSEGLPSPSG RAQPAVSPSN
QTFGQRFMGN MMGNLLVRSL TSKPKGKMDD VAPPSPAKTP EADGADKTEE EENPMMETVR
SKCITQLLLL GAIDSIQKRY WSKLQATQQI AIMDILLSLL EFASSYNSPS NLRTRMHHIP
PER
//
