ID A0A453BAB7_AEGTS Unreviewed; 1510 AA.
AC A0A453BAB7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=SEC7 domain-containing protein {ECO:0000259|PROSITE:PS50190};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET2Gv20427700.5, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET2Gv20427700.5}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EnsemblPlants; AET2Gv20427700.5; AET2Gv20427700.5; AET2Gv20427700.
DR Gramene; AET2Gv20427700.5; AET2Gv20427700.5; AET2Gv20427700.
DR Proteomes; UP000015105; Chromosome 2D.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015403; Mon2/Sec7/BIG1-like_HDS.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR032817; Mon2_C.
DR InterPro; IPR046455; Sec7/BIG1-like_C.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF312; BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 5; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF20252; BIG2_C; 1.
DR Pfam; PF16206; Mon2_C; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF09324; Sec7-like_HDS; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT DOMAIN 345..532
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 1..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1198..1243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1263..1295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1389..1408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..59
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..343
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1281..1295
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1510 AA; 167970 MW; 403320A492B317CE CRC64;
MSQASVPPAS SAVKDSPSSS TKEDSENGEI STDKQDEEKT TLGDALSMNR ASEASPTSVE
ELQNLAGGAD IKKGLEAVLD KAVELEDGKK VSGGIDLDTM NIIQRDALLL FRTLCKMSMK
EESDEVATKT RLLSLELLQG LLEGVSDLFA KNFHFIDSVK AYLSYALLRA SVSSSPVVFQ
YATRIFSVLL LRFRESLKGE IGVFFPLIVL RSLDSSDSSL SQKSSVLRML EKVCKDSQML
ADMFVNYDCD IDGPNLFERM VSALSRIAHG SQSADRAAVA SSQTVSVKGS SIQCLVSILK
SLVDWEQARR DSSNHGSVAE SHDDGASARS LATDETKVQE DGRNQFERAK AHKSTMEAAI
SEFNRKPAKG VEYLLSNKLI ENKASSVAQF LKSNASLDKV MIGEYLGQHE EFPLDVMHAY
VDSMKFSGLK FDAAIREFLK GFRLPGEAQK IDRIMEKFAE RYCADNPGLF KNADTAYILA
YAVIMLNTDA HNPMVWPKMS KSDFVRLNTA SDEEECAPKE LLEELYDSII NEEIKMKDDL
HAAKTSKVRP EIEEKGRLVN ILNLALPRLK SASDTKAESE KIIKQTQAVF KNQGQKRGVF
HVAQQVELVR PMLEAVGWPL LATFSVTMEE GDNKPRVVLC MEGFKAGIHL TRVLGMETMR
YAFLTSLVRF TFLHAPREMR SKNVEALRTL LALADMDMDA LQDAWTAVLE CVSRLEYITS
VPSMAATVMQ GSNQISRDSV VQSLKELSGK PAEQVFVNSV KLPSDSIVEF FDGLCTISAE
ELKQTPPRVF SLQKLVEISY YNMARIRLVW ARIWSVLAQH FIAAGSHHDE KVAMYAIDSL
RQLGMKYLER AELNKFTFQN DILKPFVILM RNSRSEKIRG LIVDCIVQLI KSKVGSIKSG
WRCVFMIFTA AADDENEYIV ESAFENVEQV ILEHFDQVVG DCFMDCVNCL IGFANNKCTS
RISLKAIALL RICEDRLAEG FIPGGSVKPV DVLPEANFDV TEHYWFPMLA GLSDLTLDSR
PEVRHCALEV LFDLLNERGH KFSSPFWESI FHRVLFPIFD HVRHAGRDGL SSGDDWLRDT
SIHSLQLICN LFNTFYKEVS FMLPPLLGLL LECAKKTDQT VVSIALGALV HLIEVGGHQF
SDGDWETLLK SIRDASYTTQ PLELLNSLGF QKTSNQQLLS RESETDASSY HDIREGEASI
SNNGEQEGHQ ETSPRIGLEN SEGLPSPSGR AQPAVSPSNQ TFGQRFMGNM MGNLLVRSLT
SKPKGKMDDV APPSPAKTPE ADGADKTEEE ENPMMETVRS KCITQLLLLG AIDSIQKRYW
SKLQATQQIA IMDILLSLLE FASSYNSPSN LRTRMHHIPP ERPPLNLLRQ ELAGTTIYLE
ILHKSTVHNG ANGSSEETNG SSVESDQQEK LRSLAEGKLV SFCGNILKEA SDLQPSNGET
ASADIHRVLD LRAPVIMKVL NGMCIMDAQI FKKHLREFYP LITKLICCDQ MDVRGALGDL
FSKQLTPLMP
//
