ID A0A453BF74_AEGTS Unreviewed; 1403 AA.
AC A0A453BF74;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET2Gv20484600.2, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET2Gv20484600.2}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC PRP16 sub-subfamily. {ECO:0000256|ARBA:ARBA00038040}.
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DR STRING; 200361.A0A453BF74; -.
DR EnsemblPlants; AET2Gv20484600.2; AET2Gv20484600.2; AET2Gv20484600.
DR Gramene; AET2Gv20484600.2; AET2Gv20484600.2; AET2Gv20484600.
DR OMA; VDVMFHR; -.
DR OrthoDB; 5488182at2759; -.
DR Proteomes; UP000015105; Chromosome 2D.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF91; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT DOMAIN 716..879
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 901..1081
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 41..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 415..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1362..1403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..71
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..304
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..448
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1362..1380
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1403 AA; 156864 MW; B8E7293EA977FABE CRC64;
MLYGPEVNAA NLRERSKRCL VTRAGERAAV HLSLLCFPIP KPSGGGDSNS GRPSPSPSPP
PVRPALPLRR SAPPGLPRTG SAARGSSLRP PCCRCLLAPS TSSPLLHRCT ADPSSTDHGT
APVLHQGIPS SKFLAPPLPM MSSDGRLDLD ATTSTLGPED DTAQGLILPT KDKVMYRPPP
GKSALGLDLL AHKKREKEVN NSFKRPPEKV VTAASSMDED ERPGSTENDA SSLSGVDRGI
VARRYRGTNS SEKTSSKEST VTDENERGLT PRHRDESHRQ QTPASRYEPD DDRRSRDKRG
ERETSASIGY SSSGRRGYRD DRESNSRRNE RSRSTSIDYT NKRSRDDYSS RSSRTPARSD
WDSGRWEWED TPRREYRDDR PGSQRHYPTR SPMLAAASPD ARLVSPWLGG NTPRSAASPW
DHVSPSPAPV RASGSSKGSS YSSSSGRSHL LTFSNDAEAD RSPSAADRNY DITEEMMQEM
DYNADRAWYD CEEHNTVFDG DNYAADDSSY KKKEAQLPKK LTRKDGSLMT LSQSKKLSQM
TADNAQWEDR QLLRSGAVRG TEVQTEFDDE DERKVILLVH DTKPPFLDGR VVYTKQAEPV
MPLKDPTSDM AIIARKGSVL VREIREKQSQ NKSRQRFWEL AGSNLGNILG VEKTSEQVDA
DTAVVGDQGE IDFKEEAKFS QHLKEKAEAV SDFAKSKSLS QQRQYLPIYT VRDDLLQVVR
ENQVVVVVGE TGSGKTTQLT QYLHEDGYTT TGVVGCTQPR RVAAMSVAKR VSEEMETELG
DKVGYAIRFE DVTCSSTIIK YMTDGVLLRE TLKDADLDKY RVIVMDEAHE RSLNTDVLFG
ILKKVVARRR DFKLIVTSAT LNADKFSKFF GGVPVFNIPG RTFPVNILFS KTPCEDYVEA
AVKQAMTIHI TSGPGDILIF MTGQEEIEAT CYALAERMEQ LISSSTKNVP KLSILPIYSQ
LPADLQAKIF QKAEEGTRKC IVATNIAETS LTVDGIFYVI DTGYGKMKVY NPRMGMDALQ
VFPCSRAAAD QRAGRAGRTG PGTCYRLFTE SAYQNEMLPN PVPEIQRTNL GNVVLLLKSL
KVENLLDFDF MDPPPQENIL NSMYQLWVLG ALNNVGGLTE IGWKMVEFPL DPTLAKMLLM
GEKLDCLDEV LTVVSMLSVP SVFFRPKDRA EESDAAREKF FVPESDHLTL LNVYLQWKSN
QYRGDWCNDH FLHVKGLRKA REVRSQLLDI LKALKIPLTS CHMEWDVVRK AICSAYFHNS
ARLKGIGEYV NCRNGMPCHL HPSSALYGLG YTPDYVVYHE LVLTTKEYMQ CVSAVDPQWL
AELGPMFFSV KDTDTSLLDH KKRQKEEKTA MEEEMEKLRQ EQAEAALLEK ERERRKRAKQ
QQQISMPGLK KGSTYLRPKK MGL
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