ID A0A453CAE8_AEGTS Unreviewed; 403 AA.
AC A0A453CAE8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=UDP-sugar transporter protein SLC35A4 {ECO:0008006|Google:ProtNLM};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET2Gv20783300.4, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET2Gv20783300.4}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. CMP-
CC Sialate:CMP antiporter (TC 2.A.7.12) subfamily.
CC {ECO:0000256|ARBA:ARBA00006447}.
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DR AlphaFoldDB; A0A453CAE8; -.
DR STRING; 200361.A0A453CAE8; -.
DR EnsemblPlants; AET2Gv20783300.1; AET2Gv20783300.1; AET2Gv20783300.
DR EnsemblPlants; AET2Gv20783300.2; AET2Gv20783300.2; AET2Gv20783300.
DR EnsemblPlants; AET2Gv20783300.4; AET2Gv20783300.4; AET2Gv20783300.
DR EnsemblPlants; AET2Gv20783300.8; AET2Gv20783300.8; AET2Gv20783300.
DR Gramene; AET2Gv20783300.1; AET2Gv20783300.1; AET2Gv20783300.
DR Gramene; AET2Gv20783300.2; AET2Gv20783300.2; AET2Gv20783300.
DR Gramene; AET2Gv20783300.4; AET2Gv20783300.4; AET2Gv20783300.
DR Gramene; AET2Gv20783300.8; AET2Gv20783300.8; AET2Gv20783300.
DR OMA; IYGAMNI; -.
DR OrthoDB; 315647at2759; -.
DR Proteomes; UP000015105; Chromosome 2D.
DR GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR GO; GO:0015165; F:pyrimidine nucleotide-sugar transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR007271; Nuc_sug_transpt.
DR PANTHER; PTHR10231; NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER; 1.
DR PANTHER; PTHR10231:SF96; UDP-SUGAR TRANSPORTER PROTEIN SLC35A4-RELATED; 1.
DR Pfam; PF04142; Nuc_sug_transp; 1.
DR PIRSF; PIRSF005799; UDP-gal_transpt; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 403 AA; 44596 MW; 05315100C1CCE6DC CRC64;
MQRNGVMECS VCHSKVVAGT PRSISRAYDK HKSKISSKQR VLTFLLVSGD CVLVGLQPIL
VFMCKVDGKF QFSPISVNFL TEVTKVFFAM IMLIIESRKQ KVGEKSLLSV STFVQAARNN
VLLAIPALLY AINNYLKFIM QLYFNPSTVK MLSNLKVLVI AVLLKFIMRR KFSIIQWEAL
GLLLIGISVN QLRSMPEGTK TFGLPVTAIA YIYTLIFVTV PSFASVYNEY ALKSQFDTNI
YLQNVFLYGY GAIFNLLGIL GTVIVQGPES FDILRGHSRA TFFLICNNAA QGILSSFFFK
YADTILKKYS STVATIFTGL ASAAFLGHTL TINFLLGISI VFISMHQFFS PLAKVKDDKP
AGTLELGDAQ KHRSSDSSFV NMTAGAADDA SHISDDRKPL LPI
//
