ID   A0A453CHD4_AEGTS        Unreviewed;       645 AA.
AC   A0A453CHD4;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=MIF4G domain-containing protein {ECO:0000259|SMART:SM00543};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET2Gv20846200.6, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET2Gv20846200.6}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   AlphaFoldDB; A0A453CHD4; -.
DR   EnsemblPlants; AET2Gv20846200.4; AET2Gv20846200.4; AET2Gv20846200.
DR   EnsemblPlants; AET2Gv20846200.6; AET2Gv20846200.6; AET2Gv20846200.
DR   Gramene; AET2Gv20846200.4; AET2Gv20846200.4; AET2Gv20846200.
DR   Gramene; AET2Gv20846200.6; AET2Gv20846200.6; AET2Gv20846200.
DR   Proteomes; UP000015105; Chromosome 2D.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 2.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   InterPro; IPR039762; Nmd2/UPF2.
DR   InterPro; IPR007193; Upf2/Nmd2_C.
DR   PANTHER; PTHR12839:SF10; MIF4G DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR   Pfam; PF02854; MIF4G; 2.
DR   Pfam; PF04050; Upf2; 1.
DR   SMART; SM00543; MIF4G; 2.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT   DOMAIN          1..126
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          141..342
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          360..462
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          499..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          605..628
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          557..588
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        369..383
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        408..431
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        441..462
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        501..516
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   645 AA;  73228 MW;  F9591E8D4BDD2137 CRC64;
     MKDLPSMLLS MLEEEFNFLM NKKDQIKIET KIRNIRFIGE LCKFNIAPSG LVFSCLKACL
     DDFSHHNIDV ACNLLETCGR FLYLSQGTTV RMSNMLEILR RLKNVKNLDP HHSTLVENAY
     YLCKPPERSA RVSKVRPPLH QYIRKLLFSD LDKTSVQHVL RQLRKLPWAE CEEYLVKCFL
     KVHKGKYSQV HLIALLTAGL SHYHDDFHVA VVDEVLEEIR VGLELNDYAM QQRQLAHMRF
     LGELYNYEHI DSSVIFDTLY LITVFGHGTL EQDLLDPPED FFRIRMIVTL LQTCGHYFDR
     GSSKRKLDRF LLHFQRYILN KGPLPLDVEF DVQDMFAELR PNMTRYSSPE LLASALAELE
     ENEKTKQSES AASDASCKSS ANRPDKNGRG HGEVADSESY SGSRSIYHDG SEDGDSLYEE
     NSDDRSGNGV VDDDDAMPSG SDEEERVQVR HKVVQVDPKE QEDFDRELRA LLQESLESRK
     LEPRVKSTLN MTVPMKIVEG SKDSRATERE SGEELTAEEN GNAGGGSEVK VCVRVLVKKG
     HKQQTRQMLI PGDCSLVQST KQQEAALLEE KQNIKQKILE YNEREEEEFN ASAFQTGFWG
     QGGSSAGGSI GSAGRGSWDG SNRGGRGRQR YYIAGGIYHG YGRGR
//