ID A0A453CLB4_AEGTS Unreviewed; 577 AA.
AC A0A453CLB4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=SPX domain-containing protein {ECO:0000259|PROSITE:PS51382};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET2Gv20888400.1, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET2Gv20888400.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000256|ARBA:ARBA00008335}.
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DR AlphaFoldDB; A0A453CLB4; -.
DR EnsemblPlants; AET2Gv20888400.1; AET2Gv20888400.1; AET2Gv20888400.
DR Gramene; AET2Gv20888400.1; AET2Gv20888400.1; AET2Gv20888400.
DR Proteomes; UP000015105; Chromosome 2D.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd14479; SPX-MFS_plant; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004331; SPX_dom.
DR InterPro; IPR045264; SPXM_SPX_plant.
DR PANTHER; PTHR23510; INNER MEMBRANE TRANSPORT PROTEIN YAJR; 1.
DR PANTHER; PTHR23510:SF65; SPX DOMAIN-CONTAINING MEMBRANE PROTEIN OS04G0573000; 1.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF03105; SPX; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 251..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 516..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 547..570
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..145
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT REGION 478..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 577 AA; 64975 MW; F70FD6D6056B2F11 CRC64;
MVNFGKKLMA DQVEEWKGYY INYKLMKKLL KQYVQQTQIG GKDCEQVLKE FSRILDDQIE
RIVLFLLQQQ GHLSRRIEEL GAQRAAIMQQ VDTSRVFQLR EDYREVGRDL VKLLRFVDMN
ATGLRKILKK FDKRFGYKFT DYYVTTRSNH PYSQLQQVFK QVGIVAVAGA LSRNLAYLEH
EHRGSFLSIY DNPSVVLQDP IIDQVNHAVQ KLTHATSFMQ YLGQHALIVQ DDTPSGSEDN
VDDESYHFMS LMLNLVNTFL YMVNTYIIVP TADDYSVSLG AAATVCGIII GSMAVAQVFS
SVYFSAWSNR SYFRPLVFSS IMLFSGNLLY ALAYDLNSLT VLLIGRILCG LGSARAVNRR
YISDCVPLKI RLQASAGFVS ASALGMACGP GLAGFLQTKF TIYSLTFNQS TLPGWVMSIA
WLLYLVWLWF SFKEPEHFAK AAAEAAARTS QPSESGHQES ANLEEGLAQP LLLGSEERLD
DNSEDNDDED AKSSHEPATS FASAYKLLTP SVKVQLLIYF MLKYAMEILL SESSVVTTYY
FNWDTSAVAI FLAILGLTVL PVNAIVGSYV TNWFEDR
//
