ID   A0A453CR17_AEGTS        Unreviewed;       938 AA.
AC   A0A453CR17;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=AAA+ ATPase domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET2Gv20928900.1, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET2Gv20928900.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A453CR17; -.
DR   STRING; 200361.A0A453CR17; -.
DR   EnsemblPlants; AET2Gv20928900.1; AET2Gv20928900.1; AET2Gv20928900.
DR   Gramene; AET2Gv20928900.1; AET2Gv20928900.1; AET2Gv20928900.
DR   Proteomes; UP000015105; Chromosome 2D.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   CDD; cd14798; RX-CC_like; 1.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038005; RX-like_CC.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1182; OS09G0270700 PROTEIN; 1.
DR   Pfam; PF13855; LRR_8; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT   DOMAIN          53..130
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          215..459
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   938 AA;  106689 MW;  D9F3F2183560B13D CRC64;
     GAVWRAQAAG MANYKITDGR GQPAEVVKSG IMAEGLILVV LSKITATFGG VALNAIRLKL
     GKEGNILLET ENRMKQIEIE FEIMQAFISQ VDPYSENNQI LKAWLRHIRK IASEVEDIID
     EYSFLLGKMD NAEGLLNKAL RRSKRVKAWK YISAQLKQVQ ERLQNLSTVK ERYGITVAVG
     LGGGSSRHNV TRKMYMSDSS YLNDNDNEEI IGNEDEAKKL TQCIDDDGLD RTIISICGMC
     GSGKTTLLSS IYRKQKIRKN FDCYAWITVS PNYPVEDLLS KLINQLCIPD EHAGTTDPTD
     LVDKIHSYLG NKRYLVVLDD MWNRDSWLFL ERAFVKNKCR SRVIITTRTE AVASFAEDNQ
     TIRIGLLPQR ESWDLFSRKA FSRQNRATSG CPQGLVPWAE KILERCQGLP LAIVAIGSLL
     SYREMEEHEW KLFYNQLNWQ LTNNPELNWV SSFLKLSLDD LPSHLRNCFL YCGLFPENYP
     IRRKWIIRVW VAEGFIEDRG TETTLEEVAE DYLKELAQRS LIQVTERNEY GRPKRFQVHD
     LVREMTLTIS RKERFALIWN NPDVTDGGDE ASRVSVHCGG QVFQPGPASQ HLRSFLLFDR
     NVPVPWICAA SSNFRLLRVL CLRYSLLEHI PEAITAGLFN LHYLDFSRTK VKTIPRSIAR
     LKKLQSLHLR FARVMELPRE IAMLSSLRHL SVSNDLYGTS VTGSICMLKH LQTLREVKAN
     KDLVQNLGCL TQLRSLGITA VLPSYGGDLW TSIGKMTVLT KLAVGTRGEN DEVLSLDKFK
     PLRNLEKFYL TGKLENGVLF PVSEGFDKLK VLTMRWSGLA QDPLKSLSEM GNLVYLNLYC
     AYDGESLAFC SGWFPKLKRL FLGKLDNLSS VEISDGSMTN LTYLELRELW SLEAVPEGLG
     YLRSLQHLYA RNMPRDFAAQ LEGDRKGFVQ HIANIECV
//