ID A0A453DT85_AEGTS Unreviewed; 731 AA.
AC A0A453DT85;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Disease resistance protein RPM1 {ECO:0008006|Google:ProtNLM};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET3Gv20070900.8, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET3Gv20070900.8}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR AlphaFoldDB; A0A453DT85; -.
DR EnsemblPlants; AET3Gv20070900.8; AET3Gv20070900.8; AET3Gv20070900.
DR Gramene; AET3Gv20070900.8; AET3Gv20070900.8; AET3Gv20070900.
DR Proteomes; UP000015105; Chromosome 3D.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1209; NB-ARC DOMAIN CONTAINING PROTEIN, EXPRESSED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..731
FT /note="Disease resistance protein RPM1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019096512"
FT DOMAIN 9..98
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 182..410
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 731 AA; 84653 MW; C80103625BBFC5AD CRC64;
MLEGVIWLLI LKLGDALANE AAVLGKSFLV EASALQGLFG EIRKMKEELE SMQAFFRTVE
RFKDADETTV AFVKQIRGLA FNIEDVIDEF TFKLGEDREG MFLFKAIRRV RQIKTWYRLA
NSLRDIKANL KSAAERRRRY DLKGVERDAK LTRIGSLSIR PAESVHFKRA DDLVGIAENR
DLLKKWMKDE EQRHMIITVW GMGGVGKTTL VAHVYNAIKT DFDTCAWITV SHSYEANDLL
RQIVEEFRKN DRKKEFPKDV DVTDYRSLVE TIRRYLEKKR YVLVLDDVWS VNVWFDSKDA
FFGGKLGRII FTSRIYEVAL LASEAQMINL QPLQNHYAWD LFCKEAFWKN ENRDCPPELQ
YWANKFVEKC NGLPIAIVCI GRLLSFKSAT FLEWENVYKT LELQFTNNCI LDMNIILKVS
LEDLPHNMKN CFLYCCMFPE NHVMQRKWLV RLWVAEGFIE ASEHKTLEEV AEDYLTELIN
RCLLVEVKRN ESGYVDDFQM HDILRVLALS KAREENFCIV LDYSKTNLIG KARRLSIQRG
DIAHLAESVP HLRSLLVFQN SLTFGSLRSF SRSVQLMSVL NLQDSSIESL PNEVFDLFNL
RYLGLRRTKI ANISRLIGRL QNLLVLDAWK SKITNLPVEI TRLSKLTHLI VTVKPQIPAM
QFVPSIGVPA PIGMWSLASL QTLLLVESSS EMVRYLGSLV LLRSFRISRV QGRHCEKLFK
AITNMVRLTR L
//
