ID   A0A453E496_AEGTS        Unreviewed;       873 AA.
AC   A0A453E496;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   13-SEP-2023, entry version 18.
DE   RecName: Full=DUF3741 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET3Gv20214800.24, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET3Gv20214800.24}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   AlphaFoldDB; A0A453E496; -.
DR   EnsemblPlants; AET3Gv20214800.24; AET3Gv20214800.24; AET3Gv20214800.
DR   Gramene; AET3Gv20214800.24; AET3Gv20214800.24; AET3Gv20214800.
DR   Proteomes; UP000015105; Chromosome 3D.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR   InterPro; IPR015525; BRCA2.
DR   InterPro; IPR002093; BRCA2_repeat.
DR   PANTHER; PTHR11289:SF0; BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN; 1.
DR   PANTHER; PTHR11289; BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2; 1.
DR   Pfam; PF00634; BRCA2; 6.
DR   PROSITE; PS50138; BRCA2_REPEAT; 6.
PE   4: Predicted;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REGION          253..280
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          723..742
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          755..818
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          847..873
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        253..275
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        755..806
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   873 AA;  94333 MW;  CAAE4CC18E87123B CRC64;
     GAADGCRVES MADLLVQARN TLLEGDGMSG ATVDAGQGQL FCTGSGRSVS VSERAIRRAR
     ALVGEEVEKA GNKRKQPFDD VPGAEGELRE MDAPFRGGVH NTAVPPVFQT GPGKAVLLGK
     DSIQKARAIL GERESSEMDA PFRGGVYNTT MPPVFQTGSG KAVLLGKDSI QKARVLLEDV
     DSAAGAVQPM FRTGMGRPVP VSRTSIDKAR AVLEGQTVAE KGVNGMEQFP LFQTGSGRVV
     SVSAASVQKA KSVLKDNNTS EESFGRPNQP MMFQTGSGRP AMISERSIER SRAVANEGDA
     EKSGHWDTDC QFPMFQTGLG KPVAVSWSSV QKAKAVLEEE KIKTTGRGES SDCATTLQTE
     TPTSVLMSSS LIMNSRSVTP KEDSAMQVTR TEKNHKDDDH VPLFQTGLGR SIAISKSSLK
     RASAVLEPRN IAKELEDEAH LDGAHDTPVF RTGLGRSIIA SENSRKELPI LEAEEAVKSV
     NNYNGETFVE EATFQAGIQK FVPQNRISSH KASMLLEQRN FMEKGYKDSG SQLPMFRTGS
     GKSVLISENS VQKARAVLEE QGINKDNHKL LNMDKKIPVF ASPLKTSCAR TVNISSVGVS
     RAATLLGLEE NTLSTQFFGH VGDKLGTKIN FEQENPEQRL GLASYPTENQ VHKEQHRPFE
     LSNNTVSDSG EHSIRFSTAG GRSMAISSDA LERAKSLLGE SDLMVSTNNL SYPLGSACND
     KMQNSTVAPK EGGSDLSKRR RVSGRTELAT FSHQAMSDRK DTGSFGNAVS DIHPTSENTN
     RFHVGSRSTS EIPKIVKPSS RCLSETDNTN DTKDKTRQLH MPAGALVDIS NFMGSYSGNI
     DHVVNEKRRI GGRNSASSFK RPRSSRSFDL HPC
//