ID A0A453EZW9_AEGTS Unreviewed; 1015 AA.
AC A0A453EZW9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51193};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET3Gv20526200.13, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET3Gv20526200.13}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
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DR AlphaFoldDB; A0A453EZW9; -.
DR EnsemblPlants; AET3Gv20526200.13; AET3Gv20526200.13; AET3Gv20526200.
DR Gramene; AET3Gv20526200.13; AET3Gv20526200.13; AET3Gv20526200.
DR Proteomes; UP000015105; Chromosome 3D.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd17970; DEAHc_FancJ; 1.
DR CDD; cd18788; SF2_C_XPD; 1.
DR Gene3D; 1.20.1160.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR InterPro; IPR013020; Rad3/Chl1-like.
DR NCBIfam; TIGR00604; rad3; 1.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF34; REGULATOR OF TELOMERE ELONGATION HELICASE 1; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT DOMAIN 30..318
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1015 AA; 113106 MW; 07CE4B00A0AE5F3A CRC64;
SPSPASFPIV PPTPPPSPPP AAAMPVYRIR GVDVDFPYDA YDCQITYMDR VLQSLQQGNN
ALLESPTGTG KTLCLLCSAL AWRRTFGEFL RGGGGGGGGG GSQPSGSQQS GASATQSSSY
PVIIYASRTH SQLRQVIKEL KATSYRPKMA VLGSREQMCI HEEVSKLRGK AQNNGCHYLC
KKRLCRHNNI VTDYMKNNTE LGSEPFDIED LVNIGRTKGP CPYYISRELS KSVDILFAPY
NYLIDPGNRR SLTGISWNNA VLIFDEAHNL ESICADAASF DLLTSNLTSC ITEAQECIQL
CSFKRSIENS AEKQFDPENY AILKALLMAL EKKIGELVID SKELGYTKPG SYIYEFLSEL
NITSETSKKL IETIDSASLL LEEGNSGETK AGVKAKSTVS RLETIRDMLD IIFKGGGQNH
AKYYSFHVNE SSRQTSGDSL QVFGSKASRT LSWWCFNPGL AMEEFLKLGV RSIILTSGTL
SPLDSLAMEL NLEFPVRLEN PHVISQDQIW VGVVPVGPSG HPLNSSYRTR ETVKYKQELG
TVIVNFARIV PDGLLVFFPS YSMMDKCIDY WKNRNHEHSV DDSTIWQRMC KHKQPVIEPR
QSSNFPNAIE DYAAKLRDPS TSGAIFFAVC RGKVSEGLDF ADRAGRAVIV TGMPFSTPTD
PKVRLKREYL DKQAKPSNKN PKALTGEEWY VQQAARAVNQ AVGRVIRHRH DYGAIIYCDE
RFVWPNYQSQ MSYWLKPYIK CYSKYGEVVQ TLTRFFRDKV CVDPKEMDSN DSVTPPADKC
LPQEILSDSP ATAVNEHQGT TVSLNATTRK NNYMKFTQIT PANRTTLPMK HGCSTSSQLT
SSRGQFSQDS QVVDLIDNAT MHGQLKEHTL KSMRLKKAKI ADVSSQLKHN VESRALTGNR
GQQSTPPSKR STIEQACEKN EAIQERCGGQ ESTTGPAFLK LAREKLSTAE YGEFVEFMKA
LKLKTMHIKD SLEAIAKLFS SPGRLTLLEG FRVFVSKNHL PLYEQLVRKY TMANT
//
