ID A0A453FSY1_AEGTS Unreviewed; 854 AA.
AC A0A453FSY1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=TOG domain-containing protein {ECO:0000259|SMART:SM01349};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET3Gv20769300.21, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET3Gv20769300.21}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TOG/XMAP215 family.
CC {ECO:0000256|ARBA:ARBA00025722}.
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DR AlphaFoldDB; A0A453FSY1; -.
DR EnsemblPlants; AET3Gv20769300.21; AET3Gv20769300.21; AET3Gv20769300.
DR EnsemblPlants; AET3Gv20769300.51; AET3Gv20769300.51; AET3Gv20769300.
DR Gramene; AET3Gv20769300.21; AET3Gv20769300.21; AET3Gv20769300.
DR Gramene; AET3Gv20769300.51; AET3Gv20769300.51; AET3Gv20769300.
DR Proteomes; UP000015105; Chromosome 3D.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0043232; C:intracellular non-membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0099080; C:supramolecular complex; IEA:UniProt.
DR GO; GO:0061863; F:microtubule plus end polymerase; IEA:InterPro.
DR GO; GO:0051010; F:microtubule plus-end binding; IEA:InterPro.
DR GO; GO:0030951; P:establishment or maintenance of microtubule cytoskeleton polarity; IEA:InterPro.
DR GO; GO:0046785; P:microtubule polymerization; IEA:InterPro.
DR GO; GO:0007051; P:spindle organization; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024395; CLASP_N_dom.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR034085; TOG.
DR InterPro; IPR045110; XMAP215.
DR InterPro; IPR048491; XMAP215_CLASP_TOG.
DR PANTHER; PTHR12609:SF0; CYTOSKELETON-ASSOCIATED PROTEIN 5; 1.
DR PANTHER; PTHR12609; MICROTUBULE ASSOCIATED PROTEIN XMAP215; 1.
DR Pfam; PF12348; CLASP_N; 1.
DR Pfam; PF21041; XMAP215_CLASP_TOG; 2.
DR SMART; SM01349; TOG; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..234
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 275..510
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 447..485
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 588..822
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REGION 236..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 507..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..251
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..539
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 854 AA; 93892 MW; 7040E3639A0DD5BE CRC64;
MSTEDEKLLK EAKKLPWDER LQHKNWKVRN DANIDLAALC DSITDPKDAR LREFGPLFKK
AVSDSNAPVQ EKALDALLAF QRAADADVSR YAKEVCDAIC AKCLTGRPKT VEKAQAAFLL
WVELEASEVF LESMEKAVKN KVAKAVVPAI DVMFQALSEF GAKVVPPKKI LKMLPELFDH
PDQNVRASSK GLTLELCRWI GKEPVKSILF EKMRDTMKKE LEAELANVSG IAKPTRKIRS
EQEKELEEEA VPETTGASTS EVAVPDAPME IDEYDLVDPV DILTPLEKSG FWDGVKATKW
SERRDAVAEL TKLASTKKIA PGDFNEVSRT LKKLVTDVNL AVAVEATQAI GNLAKGLRTH
FSGNSRNLLP VLLEKLKEKK PTMSEALTQT LEAMHKSGCI ALLDVIEDVR VAVKNKVPLV
RSLTLNWVAF CIETSNKATV LKLHKEYVPI CMECLNDSTP DVRDSSFSVL TAIAKMVGMK
PLERSLEKLD DVRKKKLSDM IGSATDTVLS SGTVPTSSSG AATSAREVTD SSTMRRSAAS
MLSGKKPIHA AAPAKKSGPA KSTAKKTDGG PQSKASAAPE IEDVEPSEMS LEEIEERLNS
VVKTETISQL KSTVWKERLE AIGMLKQDVE NLTELDKSAE LLVRLLCAVP GWNEKNVQVQ
QQVIEVITYI ASTVKKFPKR CVVLCLLGIS ERVADIKTRA PAMKCLTAFC EAVGPGFVFE
RLYKIMKEHK NPKVLSEGIL WMVSAVEDFG TSNLKLKDII DFCKDTGLQS SAAATRNSTI
KLIGMLHKFV GPDIKGFLSD VKPALLSALD AEYEKNPFEV CCLGHYLGFF FLLKFNCNNC
SELTGCCCSS EKNS
//
