ID   A0A453G6S2_AEGTS        Unreviewed;       625 AA.
AC   A0A453G6S2;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=DUF4220 domain-containing protein {ECO:0000259|Pfam:PF13968};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET3Gv20903800.2, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET3Gv20903800.2}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   AlphaFoldDB; A0A453G6S2; -.
DR   STRING; 200361.A0A453G6S2; -.
DR   EnsemblPlants; AET3Gv20903800.2; AET3Gv20903800.2; AET3Gv20903800.
DR   Gramene; AET3Gv20903800.2; AET3Gv20903800.2; AET3Gv20903800.
DR   OrthoDB; 345116at2759; -.
DR   Proteomes; UP000015105; Chromosome 3D.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025315; DUF4220.
DR   InterPro; IPR007658; DUF594.
DR   PANTHER; PTHR31325:SF226; GENOME ASSEMBLY, CHROMOSOME: II; 1.
DR   PANTHER; PTHR31325; OS01G0798800 PROTEIN-RELATED; 1.
DR   Pfam; PF13968; DUF4220; 1.
DR   Pfam; PF04578; DUF594; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        93..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        121..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        246..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        275..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        306..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          50..374
FT                   /note="DUF4220"
FT                   /evidence="ECO:0000259|Pfam:PF13968"
SQ   SEQUENCE   625 AA;  71341 MW;  769D001184195928 CRC64;
     MPGMEDLVKL FNVWEIQLLV LLSFTLQIFL FFTGSLRRHS SSMLLRLSIW AAYLGADFVA
     VYTLGLVSRL GDITTKGDIT TEMHTPGKIS PLAFFWAPFL LIHLAGQDTI TAFAMEDNNL
     WLRHLLNLVV QAVLAIYVFW KSIGRHSPML IVSGVFVFVV GIIKYAERTW SLKSGCYKSF
     ESSGGHHYKK LPDHDCVEDM NKDGYDDIVY IALWSTPRAH NIISGHNILS IPDDLPDWPG
     RDESKTIIKM VGIILSVMYA DLYTKALVVR TKSGIILRCI SQMSAVVAFG MFLASDKQRY
     SKTDIAITYS LFGGGFFLEL CAVFISMMSP WTWAWLKVRK WHKLAMLSWL IFSSDLGWPE
     KKQCFVKSMG QYNFSSWMTG STQARTFRQR VMAMVKWFAR LVHVEKKKIF WMSKLLDTEY
     VDVDETTMEC IAEQICLLRD HEGSTQFSSK WINWFGNIPD FGIGIVVLHL ITEKHLSEIH
     EAKSAGVGMN MMEVCRKLSR YLMYLLATHP SMLPLNASPE AIFLKDPVEL EGIVRDALDV
     VVSSNRNLLK LEELAYVWAR LLIYAAGKSR PERHMEQLGT GGELITFVWM LMYIHGLGDS
     QWRRIALGNA DDRGRRMEEV YAFPS
//