ID   A0A453GJZ5_AEGTS        Unreviewed;      1336 AA.
AC   A0A453GJZ5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=NB-ARC domain-containing protein {ECO:0000259|Pfam:PF00931};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET3Gv21059800.1, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET3Gv21059800.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   EnsemblPlants; AET3Gv21059800.1; AET3Gv21059800.1; AET3Gv21059800.
DR   EnsemblPlants; AET3Gv21059800.12; AET3Gv21059800.12; AET3Gv21059800.
DR   EnsemblPlants; AET3Gv21059800.2; AET3Gv21059800.2; AET3Gv21059800.
DR   EnsemblPlants; AET3Gv21059800.24; AET3Gv21059800.24; AET3Gv21059800.
DR   EnsemblPlants; AET3Gv21059800.4; AET3Gv21059800.4; AET3Gv21059800.
DR   Gramene; AET3Gv21059800.1; AET3Gv21059800.1; AET3Gv21059800.
DR   Gramene; AET3Gv21059800.12; AET3Gv21059800.12; AET3Gv21059800.
DR   Gramene; AET3Gv21059800.2; AET3Gv21059800.2; AET3Gv21059800.
DR   Gramene; AET3Gv21059800.24; AET3Gv21059800.24; AET3Gv21059800.
DR   Gramene; AET3Gv21059800.4; AET3Gv21059800.4; AET3Gv21059800.
DR   Proteomes; UP000015105; Chromosome 3D.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0050832; P:defense response to fungus; IEA:InterPro.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039203; RGA2/3-like.
DR   PANTHER; PTHR36766:SF55; NB-ARC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR   Pfam; PF00560; LRR_1; 3.
DR   Pfam; PF00931; NB-ARC; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT   DOMAIN          52..305
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   1336 AA;  151017 MW;  0623C5196F918C36 CRC64;
     MKTVREKIEK IEKEGQALNL VRHVARAEGS RNKETFAACS TQGMKTGMVG RDTEKEKIIN
     LLLTSEANED ISIIPIIGLG GIGKSTLAEA VLADKRVSVF DVQIWVHVSE QFDLHTIGSR
     IIRRLNSNIN LDKCDLQFIH DNLKKELSTI RYLIVLDDLW EEDGNNLEEL KRMLQYGCKG
     SRIIVTTRNQ SIVQTLSTGF LAKDQKICPV PESDQISLGV LSPDDCWEVM KQRALGPNDD
     HSGLQEIGRE IAAKCGGLPI VANALGQVMF ERRTVEAWED IRDTKVDLGL REEHQNKALE
     RLMLSYCYMK LEFKMCFTYL AVFPKGSVMD QHHLIQQWTA LGYIKAHDDG ERCINYLLGM
     SFLHISRSSS VDPGPMHAKT SQKFTMHDLV HDLASVITSK EFIILNADAT EPRGWNRARY
     CRHAQLINYQ NQTTVFKDLP PTARTLHFRY SGKLQLPKMA FSRSKYIRVL DLSGHSVGRQ
     STSSNLDLHG SSVGGQSTSS NVVLPSSIHK SKLLRYLDAT SLPITSLPKS FHTLKHMQTL
     ILSKCALETL PDTICSLNKL CYLDLSGNVS LTELPASLGK LSKLSFLNLL GCSMLQELPE
     SIYELTCLRH LDISECRTIK KLPDKFGTLL KLIFLNLSGC SKITSLPDNL RLQSLEHMNL
     SNCHELENLP KDFGNLQRLV FLSVSDCYKV SLLPESFCQL IHLKFLDLSD CHELMELPEC
     FGHLFELDSL NLTSCCKLQV LPESFCKLSK LRCLNLSYCM RLDKLPPSFG DLKLQSLDIS
     CTESLDALPN SIAEMTSLTR FEAMQGVPDV MAHVGEIKKH LLISEEIEHV VQQRENKGCS
     SIVELADLTC YELDVQELQN VKHPEDAERA KLRDKSDLRQ LSLRWGTNGG EGKSVLEKLT
     PPRTLEFFYL FGYMSKDFPK WMSDISSYLP SLTFLRLYGL GTCDTLPPFG QLPNLRCICM
     KKMPNIRKIG KEFFGHGRPC VKLRSIQLES MENLAEFLTT RSGEENEEFL IPNLHSLCLS
     NCPKLKFLPY PPRSMIWYLE NTDEIIAEGG FGKLSSSALP FEMVIKNCSF SPDNWDRLHH
     FPTLEVFQVE SCKGLRALPE VIRCFTSLKS LVLKSLKELE SLPKWLGCFI SLQRLLIQDC
     PNLTTLPESM KGLTSLTYLY IKKCQELAVL PQSLGQLITL QDISIINCPN LTTLPESMKG
     LTSLTELWIE ECQGLAMLPE CLGQMISLQI FYIIDCPNLT FLPESMKKLT ALRVLTLKEC
     QRLHMLPEWL QELTSLEEFN IMDCPNLISL PQSIQNLPVL KELYICCSPI LVERCQGEDA
     GLISHIPEVT LHVPEE
//