ID A0A453H9W5_AEGTS Unreviewed; 315 AA.
AC A0A453H9W5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=FANCL C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET4Gv20120000.24, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET4Gv20120000.24}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A453H9W5; -.
DR EnsemblPlants; AET4Gv20120000.24; AET4Gv20120000.24; AET4Gv20120000.
DR Gramene; AET4Gv20120000.24; AET4Gv20120000.24; AET4Gv20120000.
DR Proteomes; UP000015105; Chromosome 4D.
DR GO; GO:0043240; C:Fanconi anaemia nuclear complex; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0036297; P:interstrand cross-link repair; IEA:InterPro.
DR CDD; cd16490; RING-CH-C4HC3_FANCL; 1.
DR Gene3D; 3.10.110.20; RWD domain-like; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR026848; Fancl.
DR InterPro; IPR026850; FANCL_C.
DR InterPro; IPR043898; FANCL_d2.
DR InterPro; IPR044037; FANCL_d3.
DR InterPro; IPR043003; FANCL_d3_sf.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13206:SF0; E3 UBIQUITIN-PROTEIN LIGASE FANCL; 1.
DR PANTHER; PTHR13206; UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN; 1.
DR Pfam; PF11793; FANCL_C; 1.
DR Pfam; PF18890; FANCL_d2; 1.
DR Pfam; PF18891; FANCL_d3; 1.
DR SMART; SM01197; FANCL_C; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT DOMAIN 47..127
FT /note="FANCL UBC-like"
FT /evidence="ECO:0000259|Pfam:PF18890"
FT DOMAIN 132..227
FT /note="FANCL UBC-like"
FT /evidence="ECO:0000259|Pfam:PF18891"
FT DOMAIN 237..312
FT /note="FANCL C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11793"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 315 AA; 35218 MW; 5887ADC0A89E69D0 CRC64;
SSHGATRHPL SRRRSSLAPF AGRPGGSGAA APAQTARVLQ LRVRAAQIEE VGWGQLVSAT
GDDGVSCLTF RVMDEQRRHH LLEITLPMNY PACPPSIAAD VPYLPKLQWS ESSRLKDVLC
QFQEHLKVLQ DYWSTMDGID KALWVVDPTK PTYAMSHHRI ALGDDCYILL HVDTHKPNSL
PECRFLGTDG KLERLIKNWR KNRKRWSADR KFHENLATVL DFALPQPPSV SIKDDQQADC
GICYATHLPV DDELGTQSGC AADYKCENPS CSRAFHSVCL RDWLRTITTT RQSFDVLFGN
CPYCSEPVAV KSTDS
//
